Results 61 to 70 of about 168,114 (189)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec +6 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan +5 more
wiley +1 more source
MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru +13 more
wiley +1 more source
, 2020 Increased expression of the retroviruses of HERV-W family has been linked to multiple sclerosis (MS) pathophysiology; nothing is known at the moment about MOG-IgG associated disorders.
Bo M. +10 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang +23 more
wiley +1 more source
Anti-B-cell therapy in patients with neuromyelitis optica spectrum disorders
Неврология, нейропсихиатрия, психосоматика, 2021 Neuromyelitis optica spectrum disorders (NMOSDs) are a group of central nervous system autoimmune diseases characterized by similar clinical manifestations, optic neuritis, and transverse myelitis being the most frequent among them.
S. V. Kotov, E. S. Novikova, A. S. Kotov
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Seroprevalence and clinical phenotype of MOG-IgG-associated disorders in Sri Lanka [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 2019 Antibodies targeting myelin oligodendrocyte glycoprotein immunoglobulin (MOG-IgG) detected by cell-based assays1 are recognised biomarkers of a subgroup of central nervous system inflammatory demyelinating disorders (CNS IDDs) termed MOG-IgG-associated disorders (MOGAD).2 Single episode and recurrent ON are the most common presentations of MOGAD ...
Bimsara Senanayake +12 more
openaire +2 more sources
, 2018 Supplemental material for MOG-IgG-associated disease has a stereotypical clinical course, asymptomatic visual impairment and good treatment response by Lekha Pandit, Sharik Mustafa, Ichiro Nakashima, Toshyuki Takahashi and Kimhiko Kaneko in Multiple ...
Ichiro Nakashima (3574049) +4 more
core +1 more source
Journal of Neuroinflammation, 2011 Background Serum autoantibodies against the water channel aquaporin-4 (AQP4) are important diagnostic biomarkers and pathogenic factors for neuromyelitis optica (NMO).
Mader Simone +19 more
doaj +1 more source