Results 11 to 20 of about 3,487 (207)

Longitudinal Retinal Changes in MOGAD [PDF]

Annals of Neurology, 2022
ObjectivePatients with myelin oligodendrocyte glycoprotein antibody (MOG‐IgG)‐associated disease (MOGAD) suffer from severe optic neuritis (ON) leading to retinal neuro‐axonal loss, which can be quantified by optical coherence tomography (OCT). We assessed whether ON‐independent retinal atrophy can be detected in MOGAD.MethodsEighty patients with MOGAD
Oertel, Frederike Cosima, Sotirchos, Elias S., Zimmermann, Hanna G., Motamedi, Seyedamirhosein, Specovius, Svenja, Asseyer, Eva Susanna, Chien, Claudia, Cook, Lawrence, Vasileiou, Eleni, Filippatou, Angeliki, Calabresi, Peter A., Saidha, Shiv, Pandit, Lekha, D’Cunha, Anitha, Outteryck, Olivier, Zéphir, Hélène, Pittock, Sean, Flanagan, Eoin P., Bhatti, M. Tariq, Rommer, Paulus S., Bsteh, Gabriel, Zrzavy, Tobias, Kuempfel, Tania, Aktas, Orhan, Ringelstein, Marius, Albrecht, Philipp, Ayzenberg, Ilya, Pakeerathan, Thivya, Knier, Benjamin, Aly, Lilian, Asgari, Nasrin, Soelberg, Kerstin, Marignier, Romain, Tilikete, Caroline Froment, Cobo Calvo, Alvaro, Villoslada, Pablo, Sanchez-Dalmau, Bernardo, Martinez-Lapiscina, Elena H., Llufriu, Sara, Green, Ari J., Yeaman, Michael R., Smith, Terry J., Brandt, Alexander U., Chen, John, Paul, Friedemann, Havla, Joachim, Altintas, Ayse   +46 more
core   +9 more sources

Delimiting MOGAD as a disease entity using translational imaging [PDF]

Frontiers in Neurology, 2023
The first formal consensus diagnostic criteria for myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) were recently proposed. Yet, the distinction of MOGAD-defining characteristics from characteristics of its important differential ...
Frederike Cosima Oertel, Frederike Cosima Oertel, Frederike Cosima Oertel, Maria Hastermann, Maria Hastermann, Friedemann Paul, Friedemann Paul, Friedemann Paul   +7 more
doaj   +4 more sources

Diagnostic criteria for MOGAD [PDF]

Journal of Neurology
Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare antibody-mediated inflammatory demyelinating disorder of the central nervous system with a broad clinical spectrum.
Voase, Sophie, Robertson, Neil P.
openaire   +3 more sources

MOG CNS Autoimmunity and MOGAD [PDF]

Neurology Neuroimmunology & Neuroinflammation
At one time considered a possible form of neuromyelitis optica (NMO) spectrum disorder (NMOSD), it is now accepted that myelin oligodendrocyte glycoprotein (MOG) antibody (Ab)-associated disorder (MOGAD) is a distinct entity from either NMO or multiple sclerosis (MS) and represents a broad spectrum of clinical phenotypes.
Carson E. Moseley, Akash Virupakshaiah, Thomas G. Forsthuber, Lawrence Steinman, Emmanuelle Waubant, Scott S. Zamvil   +5 more
openaire   +5 more sources

MOG antibody associated disorder (MOGAD)

Advances in Clinical Neuroscience & Rehabilitation, 2021
The existence of antibodies to myelin oligodendrocyte glycoprotein (MOG) in some patients with CNS demyelinating disease has been recognised for 30 years, but their clinical utility as biomarkers, and potential pathogenicity in humans has only become apparent in the past 15 years. The advent of more precise live cell-based assays for antibody detection
Lilley Kate, Sudarshini Ramanathan, Russell C Dale, Fabienne Brilot, Simon Broadley   +4 more
openaire   +3 more sources

The Clinical and Radiologic Features of Patients with Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-Associated Disease (MOGAD) in the City of Sakarya, Türkiye

Gazi Medical Journal
Objective: The study aims to share our knowledge on myelin oligodendrocyte glycoprotein antibody (anti-MOG) seropositivity in patients with demyelinating diseases, focusing on their clinical, serologic, and radiologic characteristics, as well as ...
Saadet Sayan, Esen Çiçekli, Onur Taydaş, Mohammadreza Yousefi, Tansu Doran, Dilcan Kotan   +5 more
doaj   +2 more sources

Attack phenotypes and disease course in pediatric MOGAD

Annals of Clinical and Translational Neurology, 2023
AbstractMyelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) is an autoimmune demyelinating condition that affects children differently than adults. We performed a literature review to assess the presentation and clinical course of pediatric MOGAD.
Jonathan D. Santoro, Timothy Beukelman, Cheryl Hemingway, Suvi R. K. Hokkanen, Frank Tennigkeit, Tanuja Chitnis   +5 more
openaire   +4 more sources

NMOSD and MOGAD: an evolving disease spectrum

Nature Reviews Neurology
Neuromyelitis optica (NMO) spectrum disorder (NMOSD) is a relapsing inflammatory disease of the CNS, characterized by the presence of serum aquaporin 4 (AQP4) autoantibodies (AQP4-IgGs) and core clinical manifestations such as optic neuritis, myelitis, and brain or brainstem syndromes.
Akiyuki Uzawa, Frederike Cosima Oertel, Masahiro Mori, Friedemann Paul, Satoshi Kuwabara   +4 more
openaire   +3 more sources

A Lethal Progressive Neuroinflammation Disguised as MOGAD Revealing a Final Diagnosis of Griscelli Syndrome. [PDF]

Ann Clin Transl Neurol
Annals of Clinical and Translational Neurology, Volume 13, Issue 8, Page 1740-1742, August 2026.
Veredice C, Arpaia C, Contaldo I, Capasso A, Rigante D.   +4 more
europepmc   +2 more sources

A study of referral bias in NMOSD and MOGAD cohorts [PDF]

Multiple Sclerosis and Related Disorders
Neuromyelitis optica spectrum disorder (NMOSD) and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are rare disorders often seen in highly specialized services or tertiary centres. We aimed to assess if cohort characteristics depend on the origin of the referral catchment areas serviced by our centre (i.e.
Miguel Leal Rato, Bo Chen, Anna Francis, Silvia Messina, Madalina Miron, Yvonne Sharawakanda, Eoin O'Sullivan, Sarah Cooper, Leonora Fisniku, Christopher Halfpenny, Roswell Martin, Jeremy Hobart, Waqar Rashid, Cheryl Hemingway, Victoria Williams, Yael Hacohen, Ruth Dobson, Sithara Ramdas, Maria Isabel Leite, Jacqueline Palace, Ruth Geraldes   +20 more
openaire   +5 more sources