Results 161 to 170 of about 6,155,889 (255)

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Nucleic acid aptamers: new methods for selection, target validation, molecular diagnostics and therapeutics. [PDF]

Signal Transduct Target Ther
Ji DK, Lei H, Liu J, Xia F, Gao X, Zhou YQ, Li R, Han Y, Wang R, Tan W.   +9 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Distance analysis of 220 parsley genotypes (Petroselinum crispum (Mill.) Nyman) using RAPD-, dpRAPD- and SRAP-markers

, 2008
Ulrich, Detlef, Lohwasser, Ulrike, Marthe, Frank, Struckmeyer, Tobias, Budahn, Holger, Krüger, Hans   +5 more
core  

Amylose content in rice: integrating genetics, grain filling physiology, and breeding strategies. [PDF]

Front Plant Sci
Usenbekov B, Meldebekova A, Sartbayeva I, Amirova A, Atabayeva S, Usenbekov N, Mynbayeva D, Kurbangaliyeva T.   +7 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Carrot (Daucus carota L.) linkage map based on double mutant F2 population

, 2008
Nothnagel, Thomas, Baranski, Rafal, Grzebelus, D., Schrader, Otto, Kielkowska, A.   +4 more
core  

Innovations in Aptamer Technology: SELEX To Intelligent Molecular Engineering and Clinical Translation. [PDF]

FASEB J
Mehmood A, Din MU, Shah SK, Munawer MF, Marryum M, Jiang H, Liu X, Wang X.   +7 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

QTLs for Sharka resistance in apricot

, 2008
VIVOLI D, PALMISANO F, TESTOLIN R., RIZZO M, CASTELLANO M. A, DONDINI L, LAIN O, BASSI D, ADAMI M, BOSCIA D, MINAFRA A, GEUNA F, TARTARINI S, SAVINO, Vito Nicola, BAZZONI A   +14 more
core