Results 81 to 90 of about 14,384,780 (329)
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells [PDF]
Sorafenib is the unique accepted molecular targeted drug for the treatment of patients in advanced stage of hepatocellular carcinoma. The current study evaluated cell signaling regulation of endoplasmic reticulum (ER) stress, c-Jun-N-terminal kinase (JNK)
Contreras Bernal, Laura +8 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Full-Genome Deep Sequencing and Phylogenetic Analysis of Novel Human Betacoronavirus
A novel betacoronavirus associated with lethal respiratory and renal complications was recently identified in patients from several countries in the Middle East.
Matthew Cotten +11 more
doaj +1 more source
Quantum transport through molecular wires
We explore electron transport properties in molecular wires made of heterocyclic molecules (pyrrole, furan and thiophene) by using the Green's function technique. Parametric calculations are given based on the tight-binding model to describe the electron
Cronenwett S. M. +4 more
core +1 more source
AbstractMore than a century ago, Ernst Haeckel created embryo drawings to illustrate the morphological similarity of vertebrate early embryos. These drawings have been both widely presented and frequently criticized. At the same time that the idea of morphological similarity was recently attacked, there has been a growing realization of molecular ...
Richard P, Elinson, Lorren, Kezmoh
openaire +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Molecular Dynamics Simulation of Sympathetic Crystallization of Molecular Ions
It is shown that the translational degrees of freedom of a large variety of molecules, from light diatomic to heavy organic ones, can be cooled sympathetically and brought to rest (crystallized) in a linear Paul trap.
A. Fioretti +31 more
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Molecular gas and triggered star formation surrounding Wolf-Rayet stars
The environments surrounding nine Wolf-Rayet stars were studied in molecular emission. Expanding shells were detected surrounding these WR stars (see left panels of Figure 1). The average masses and radii of the molecular cores surrounding these WR stars
Liu, Tie, Wu, Yuefang, Zhang, Huawei
core +1 more source

