Results 91 to 100 of about 7,530,679 (394)

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

FEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley, Daniel H. Shain, Eric A. Klein   +2 more
wiley   +1 more source

Dot6/Tod6 degradation fine-tunes the repression of ribosome biogenesis under nutrient-limited conditions

iScience, 2022
Summary: Ribosome biogenesis (Ribi) is a complex and energy-consuming process, and should therefore be repressed under nutrient-limited conditions to minimize unnecessary cellular energy consumption. In yeast, the transcriptional repressors Dot6 and Tod6
Kino Kusama, Yuta Suzuki, Ena Kurita, Tomoyuki Kawarasaki, Keisuke Obara, Fumihiko Okumura, Takumi Kamura, Kunio Nakatsukasa   +7 more
doaj  

Quantum Biology at the Cellular Level - elements of the research program [PDF]

arXiv, 2013
Quantum Biology is emerging as a new field at the intersection between fundamental physics and biology, promising novel insights into the nature and origin of biological order. We discuss several elements of QBCL (Quantum Biology at Cellular Level), a research program designed to extend the reach of quantum concepts to higher than molecular levels of ...
arxiv  

Gametocytes: insights gained during a decade of molecular monitoring [PDF]

, 2008
In vertebrate hosts, malaria parasites produce specialized male and female sexual stages (gametocytes). Soon after being taken up by a mosquito, gametocytes rapidly produce gametes and, once mated, they infect their vector and can be transmitted to new ...
Abdel-Wahab, Akim, Alano, Ali, Babiker, Babiker, Babiker, Babiker, Bell, Billingsley, Bonnet, Boudin, Bousema, Bousema, Bousema, Buckling, Buckling, Buckling, de Roode, Dixon, Drakeley, Drew, Dunyo, Dye, El-Sayed, Farnert, Farnert, Ferguson, Gaillard, Gardner, Gautret, Graves, Hamza A. Babiker, Hill, Huber, Jarvi, Jeffery, Kooij, Menegon, Mideo, Nassir, Nee, Niederwieser, Nwakanma, Okell, Osorio, Ouédraogo, Paganotti, Paul, Paul, Paul, Paul, Petra Schneider, Pichon, Pradel, Read, Reece, Reece, Robert, Sarah E. Reece, Schall, Schall, Schneider, Schneider, Schneider, Shekalaghe, Shekalaghe, Shutler, Shutler, Smith, Sokhna, Sowunmi, Talman, Talman, Targett, Trager, Vardo, Wargo, Wargo, Wargo, Werren, West   +81 more
core   +2 more sources

The UMBRELLA SIOP–RTSG 2016 Wilms tumour pathology and molecular biology protocol

Nature reviews. Urology, 2018
On the basis of the results of previous national and international trials and studies, the Renal Tumour Study Group of the International Society of Paediatric Oncology (SIOP–RTSG) has developed a new study protocol for paediatric renal tumours: the ...
G. Vujanić, M. Gessler, A. Ooms, P. Collini, A. Coulomb-L'Hermine, Ellen D'Hooghe, R. D. de Krijger, D. Perotti, K. Pritchard-Jones, C. Vokuhl, M. V. D. van den Heuvel-Eibrink, N. Graf   +11 more
semanticscholar   +1 more source

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

FEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri, Haruka Tachibana, Daisuke Kawasaki, Taichi Chisuga, Toma Kashima, Shinya Fushinobu, Fumitaka Kudo, Tadashi Eguchi, Akimasa Miyanaga   +8 more
wiley   +1 more source

Genomics and proteomics: a signal processor's tour [PDF]

, 2004
The theory and methods of signal processing are becoming increasingly important in molecular biology. Digital filtering techniques, transform domain methods, and Markov models have played important roles in gene identification, biological sequence ...
Vaidyanathan, P. P.
core   +2 more sources

Molecular biology of neuroblastoma

Clinical and Translational Oncology, 2007
Neuroblastoma is one of the most frequently occurring solid tumours in children, especially in the first year of life, when it accounts for 50% of all tumours. It is the second most common cause of death in children, only preceded by accidents. The most peculiar characteristic of neuroblastoma is its clinical heterogeneity.
Elena Grau, Rosa Noguera, Victoria Castel, Francisco Martínez   +3 more
openaire   +3 more sources

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, EarlyView.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

Computer algebra in systems biology [PDF]

arXiv, 2007
Systems biology focuses on the study of entire biological systems rather than on their individual components. With the emergence of high-throughput data generation technologies for molecular biology and the development of advanced mathematical modeling techniques, this field promises to provide important new insights.
arxiv