Results 31 to 40 of about 7,530,679 (394)
DAMBE7: New and Improved Tools for Data Analysis in Molecular Biology and Evolution
DAMBE is a comprehensive software package for genomic and phylogenetic data analysis on Windows, Linux, and Macintosh computers. New functions include imputing missing distances and phylogeny simultaneously (paving the way to build large phage and ...
X. Xia
semanticscholar +1 more source
Asymmetric inheritance of RNA toxicity in C. elegans expressing CTG repeats
Summary: Nucleotide repeat expansions are a hallmark of over 40 neurodegenerative diseases and cause RNA toxicity and multisystemic symptoms that worsen with age.
Maya Braun+8 more
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Erwin Schroedinger, Francis Crick and epigenetic stability [PDF]
Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology.
Ogryzko, Vasily
core +4 more sources
DAMBE: software package for data analysis in molecular biology and evolution.
DAMBE (data analysis in molecular biology and evolution) is an integrated software package for converting, manipulating, statistically and graphically describing, and analyzing molecular sequence data with a user-friendly Windows 95/98/2000/NT interface.
X. Xia, Z. Xie
semanticscholar +1 more source
New binding specificities evolve via point mutation in an invertebrate allorecognition gene
Summary: Many organisms use genetic self-recognition systems to distinguish themselves from conspecifics. In the cnidarian, Hydractinia symbiolongicarpus, self-recognition is partially controlled by allorecognition 2 (Alr2).
Aidan L. Huene+2 more
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A Molecular Implementation of the Least Mean Squares Estimator [PDF]
In order to function reliably, synthetic molecular circuits require mechanisms that allow them to adapt to environmental disturbances. Least mean squares (LMS) schemes, such as commonly encountered in signal processing and control, provide a powerful means to accomplish that goal.
arxiv +1 more source
TGFβ2 and TGFβ3 mediate appropriate context-dependent phenotype of rat valvular interstitial cells
Summary: This study focused on characterizing the potential mechanism of valvular toxicity caused by TGFβ receptor inhibitors (TGFβRis) using rat valvular interstitial cells (VICs) to evaluate early biological responses to TGFβR inhibition. Three TGFβRis
Faye Wang+12 more
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On Some Recent Insights in Integral Biomathics [PDF]
This paper summarizes the results in Integral Biomathics obtained to this moment and provides an outlook for future research in the field.
arxiv +1 more source
Structural biology: a century-long journey into an unseen world [PDF]
© Institute of Materials, Minerals and Mining 2015.When the first atomic structures of salt crystals were determined by the Braggs in 1912–1913, the analytical power of X-ray crystallography was immediately evident. Within a few decades the technique was
Curry, S
core +1 more source
Summary: Mutations in all subtypes of the inositol 1,4,5-trisphosphate receptor Ca2+ release channel are associated with human diseases. In this report, we investigated the functionality of three neuropathy-associated missense mutations in IP3R3 (V615M ...
Lara E. Terry+10 more
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