Results 31 to 40 of about 1,882,127 (209)

Establishment of a primary porcine retinal pigment epithelium monolayer to complement retinal ex vivo cultures

open access: yesSTAR Protocols, 2023
Summary: Impaired function of the retinal pigment epithelium (RPE) resembles a hallmark in many retinal diseases; thus, co-cultivation models with RPE and retinal explants are useful to investigate these.
Agnes Fietz   +3 more
doaj   +1 more source

A desmosomal cadherin controls multipotent hair follicle stem cell quiescence and orchestrates regeneration through adhesion signaling

open access: yesiScience, 2023
Summary: Stem cells (SCs) are critical to maintain tissue homeostasis. However, it is currently not known whether signaling through cell junctions protects quiescent epithelial SC reservoirs from depletion during disease-inflicted damage.
William V.J. Hariton   +11 more
doaj   +1 more source

Intracellular lactate dynamics in Drosophila neurons

open access: yesiScience
Summary: Rates of lactate production and consumption reflect the metabolic state of many cell types, including neurons. Here, we investigated the effects of nutrient deprivation on lactate dynamics in Drosophila neurons by leveraging the limiting effects
Matthew S. Price   +5 more
doaj   +1 more source

Molecular biology: Self-sustaining chemistry

open access: yesChemistry Central Journal, 2007
Molecular biology is an established interdisciplinary field within biology that deals fundamentally with the function of any nucleic acid in the cellular context.
Wrede Paul
doaj   +1 more source

eIF4E phosphorylation recruits β-catenin to mRNA cap and promotes Wnt pathway translation in dentate gyrus LTP maintenance

open access: yesiScience, 2023
Summary: The mRNA cap-binding protein, eukaryotic initiation factor 4E (eIF4E), is crucial for translation and regulated by Ser209 phosphorylation. However, the biochemical and physiological role of eIF4E phosphorylation in translational control of long ...
Sudarshan Patil   +7 more
doaj   +1 more source

The Molecular Biology of Ilarviruses

open access: yes, 2013
Ilarviruses were among the first 16 groups of plant viruses approved by ICTV. Like Alfalfa mosaic virus (AMV), bromoviruses, and cucumoviruses they are isometric viruses and possess a single-stranded, tripartite RNA genome. However, unlike these other three groups, ilarviruses were recognized as being recalcitrant subjects for research (their ready ...
Pallás Benet, Vicente   +4 more
openaire   +4 more sources

Evaluation of colloidal platinum on cytotoxicity, oxidative stress and barrier permeability across the gut epithelium

open access: yesHeliyon, 2019
Colloidal platinum (Pt) is widely consumed due to its health promoting benefits. However, the exact biological effects of these nanoparticles have not been studied in detail, particularly in the gut. In the present study we observed that colloidal Pt was
Sinem Tunçer   +5 more
doaj   +1 more source

The Application of Molecular Biology [PDF]

open access: yesCurrent Issues in Molecular Biology, 1999
Molecular biology methods have tremendous value not only in the investigation of basic scientific questions, but also in application to a wide variety of problems affecting the overall human condition. Disease prevention and treatment, generation of new protein products, and manipulation of plants and animals for desired phenotypic traits are all ...
openaire   +3 more sources

Molecular biology of erythropoietin

open access: yesKidney International, 1993
A 42-year-old man presented with hypertension and proteinuria 22 years ago and was found to have adult polycystic kidney disease. Within 8 years he was approaching end-stage renal failure (creatinine clearance, 10 mI/mm). The hemoglobin (Hb) was 10.0 g/dl. Hemodialysis was initiated 13 years ago, when his Hb was 6.6 g/dl. Two months later, it had risen
openaire   +3 more sources

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