Results 31 to 40 of about 7,995,512 (394)

Molecular Biology of Osteosarcoma

open access: yesCancers, 2020
Osteosarcoma (OS) is the most frequent primary bone cancer in children and adolescents and the third most frequent in adults. Many inherited germline mutations are responsible for syndromes that predispose to osteosarcomas including Li Fraumeni syndrome,
A. Czarnecka   +7 more
semanticscholar   +1 more source

Cytoplasmic and mitochondrial aminoacyl-tRNA synthetases differentially regulate lifespan in Caenorhabditis elegans

open access: yesiScience, 2022
Summary: Reducing the rate of translation promotes longevity in multiple organisms, representing a conserved mechanism for lifespan extension. Aminoacyl-tRNA synthetases (ARSs) catalyze the loading of amino acids to their cognate tRNAs, thereby playing ...
Tianlin Zheng   +7 more
doaj   +1 more source

Bioinformatics Databases: State of the Art and Research Perspectives [PDF]

open access: yes, 2003
Bioinformatics or computational biology, i.e. the application of mathematical and computer science methods to solving problems in molecular biology that require large scale data, computation, and analysis, is a research area currently receiving a ...
Bry, François, Kröger, Peer
core   +2 more sources

RPRM negatively regulates ATM levels through its nuclear translocation on irradiation mediated by CDK4/6 and IPO11

open access: yesiScience, 2022
Summary: How the ataxia telangiectasia mutated (ATM) protein kinase, a core protein in DNA damage response, is regulated at post-transcription level remains unclear.
Yarui Zhang   +8 more
doaj   +1 more source

Molecular biology of hearing [PDF]

open access: yesLaryngo- rhino- otologie, 2011
GMS Current Topics in Otorhinolaryngology - Head and Neck Surgery; 10:Doc06; ISSN 1865 ...
Stöver, Timo, Diensthuber, Marc
openaire   +5 more sources

Molecular Biology or Ultrastructural Biology ? [PDF]

open access: yesNature, 1961
IN a recent communication1, Prof. C. H. Waddington protests against the increasing use of the name ‘molecular biology’ for a large and ever-growing field to which, he argues, it does not apply, and suggests confining it to more restricted topics for which in any event a better name would be ‘ultra-structural biology’.
openaire   +4 more sources

Developing Predictive Molecular Maps of Human Disease through Community-based Modeling [PDF]

open access: yes, 2011
The failure of biology to identify the molecular causes of disease has led to disappointment in the rate of development of new medicines. By combining the power of community-based modeling with broad access to large datasets on a platform that promotes ...
Christine Suver   +10 more
core   +2 more sources

DAMBE7: New and Improved Tools for Data Analysis in Molecular Biology and Evolution

open access: yesMolecular biology and evolution, 2018
DAMBE is a comprehensive software package for genomic and phylogenetic data analysis on Windows, Linux, and Macintosh computers. New functions include imputing missing distances and phylogeny simultaneously (paving the way to build large phage and ...
X. Xia
semanticscholar   +1 more source

Phosphate-induced activation of VEGFR2 leads to caspase-9-mediated apoptosis of hypertrophic chondrocytes

open access: yesiScience, 2023
Summary: Low circulating phosphate (Pi) leads to rickets, characterized by expansion of the hypertrophic chondrocytes (HCs) in the growth plate due to impaired HC apoptosis.
Prem Swaroop Yadav   +3 more
doaj   +1 more source

Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease [PDF]

open access: yes, 2015
Copyright © 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.Peer reviewedPublisher ...
Clunas, Scott   +14 more
core   +1 more source

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