Results 31 to 40 of about 7,530,679 (394)

DAMBE7: New and Improved Tools for Data Analysis in Molecular Biology and Evolution

open access: yesMolecular biology and evolution, 2018
DAMBE is a comprehensive software package for genomic and phylogenetic data analysis on Windows, Linux, and Macintosh computers. New functions include imputing missing distances and phylogeny simultaneously (paving the way to build large phage and ...
X. Xia
semanticscholar   +1 more source

Asymmetric inheritance of RNA toxicity in C. elegans expressing CTG repeats

open access: yesiScience, 2022
Summary: Nucleotide repeat expansions are a hallmark of over 40 neurodegenerative diseases and cause RNA toxicity and multisystemic symptoms that worsen with age.
Maya Braun   +8 more
doaj  

Erwin Schroedinger, Francis Crick and epigenetic stability [PDF]

open access: yes, 2008
Schroedinger's book 'What is Life?' is widely credited for having played a crucial role in development of molecular and cellular biology. My essay revisits the issues raised by this book from the modern perspective of epigenetics and systems biology.
Ogryzko, Vasily
core   +4 more sources

DAMBE: software package for data analysis in molecular biology and evolution.

open access: yesJournal of Heredity, 2001
DAMBE (data analysis in molecular biology and evolution) is an integrated software package for converting, manipulating, statistically and graphically describing, and analyzing molecular sequence data with a user-friendly Windows 95/98/2000/NT interface.
X. Xia, Z. Xie
semanticscholar   +1 more source

New binding specificities evolve via point mutation in an invertebrate allorecognition gene

open access: yesiScience, 2021
Summary: Many organisms use genetic self-recognition systems to distinguish themselves from conspecifics. In the cnidarian, Hydractinia symbiolongicarpus, self-recognition is partially controlled by allorecognition 2 (Alr2).
Aidan L. Huene   +2 more
doaj  

A Molecular Implementation of the Least Mean Squares Estimator [PDF]

open access: yes2016 IEEE 55th Conference on Decision and Control (CDC), 2017
In order to function reliably, synthetic molecular circuits require mechanisms that allow them to adapt to environmental disturbances. Least mean squares (LMS) schemes, such as commonly encountered in signal processing and control, provide a powerful means to accomplish that goal.
arxiv   +1 more source

TGFβ2 and TGFβ3 mediate appropriate context-dependent phenotype of rat valvular interstitial cells

open access: yesiScience, 2021
Summary: This study focused on characterizing the potential mechanism of valvular toxicity caused by TGFβ receptor inhibitors (TGFβRis) using rat valvular interstitial cells (VICs) to evaluate early biological responses to TGFβR inhibition. Three TGFβRis
Faye Wang   +12 more
doaj  

On Some Recent Insights in Integral Biomathics [PDF]

open access: yesProgress in Biophysics and Molecular Biology, Vol. 113, Issues 1, 2013, pp. 216-228, 2013
This paper summarizes the results in Integral Biomathics obtained to this moment and provides an outlook for future research in the field.
arxiv   +1 more source

Structural biology: a century-long journey into an unseen world [PDF]

open access: yes, 2015
© Institute of Materials, Minerals and Mining 2015.When the first atomic structures of salt crystals were determined by the Braggs in 1912–1913, the analytical power of X-ray crystallography was immediately evident. Within a few decades the technique was
Curry, S
core   +1 more source

Missense mutations in inositol 1,4,5-trisphosphate receptor type 3 result in leaky Ca2+ channels and activation of store-operated Ca2+ entry

open access: yesiScience, 2022
Summary: Mutations in all subtypes of the inositol 1,4,5-trisphosphate receptor Ca2+ release channel are associated with human diseases. In this report, we investigated the functionality of three neuropathy-associated missense mutations in IP3R3 (V615M ...
Lara E. Terry   +10 more
doaj  

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