Results 31 to 40 of about 7,702,303 (369)

Formal molecular biology

open access: yesTheoretical Computer Science, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
DANOS V., LANEVE, COSIMO
openaire   +2 more sources

A Molecular Biology Database Digest [PDF]

open access: yes, 2000
Computational Biology or Bioinformatics has been defined as the application of mathematical and Computer Science methods to solving problems in Molecular Biology that require large scale data, computation, and analysis [18].
Bry, François, Kröger, Peer
core   +2 more sources

Molecular biology of the gut [PDF]

open access: yesMolecular and Cellular Pediatrics, 2016
Editorial The gastrointestinal tract is the largest exposed surface among mammalian macroorganisms. It is constantly exposed to substantial challenges and exerts a potpourri of diverse physiological functions. Among the major intestinal functions is the digestion of nutrients and subsequent uptake and metabolism of their respective building blocks ...
Buford L. Nichols   +2 more
openaire   +3 more sources

Molecular Biology of Aging [PDF]

open access: yesCell, 1999
1. The Human Mitochondrion and Pathophysiology of Aging and Age-related Diseases D.C. Wallace 2. Sirtuins: A Universal Link between NAD, Metabolism, and Aging S.-i. Imai and L. P. Guarente 3. Calorie Restriction in Lower Organisms S.L. Helfand, J.H. Bauer, and J.G. Wood 4. Evolutionary Theory in Aging Research S.N. Austad and T.B.L. Kirkwood 5.
David A. Sinclair   +2 more
openaire   +3 more sources

Prolyl endopeptidase-like is a (thio)esterase involved in mitochondrial respiratory chain function

open access: yesiScience, 2021
Summary: Deficiency of the serine hydrolase prolyl endopeptidase-like (PREPL) causes a recessive metabolic disorder characterized by neonatal hypotonia, feeding difficulties, and growth hormone deficiency.
Karen Rosier   +21 more
doaj  

DAMBE7: New and Improved Tools for Data Analysis in Molecular Biology and Evolution

open access: yesMolecular biology and evolution, 2018
DAMBE is a comprehensive software package for genomic and phylogenetic data analysis on Windows, Linux, and Macintosh computers. New functions include imputing missing distances and phylogeny simultaneously (paving the way to build large phage and ...
X. Xia
semanticscholar   +1 more source

Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC protein

open access: yesiScience, 2022
Summary: The XPC protein complex plays a central role in DNA lesion recognition for global genome nucleotide excision repair (GG-NER). Lesion recognition can be accomplished in either a UV-DDB-dependent or -independent manner; however, it is unclear how ...
Masayuki Kusakabe   +13 more
doaj  

Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease [PDF]

open access: yes, 2015
Copyright © 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.Peer reviewedPublisher ...
Clunas, Scott   +14 more
core   +1 more source

Conditional deletion of LRRC8A in the brain reduces stroke damage independently of swelling-activated glutamate release

open access: yesiScience, 2023
Summary: The ubiquitous volume-regulated anion channels (VRACs) facilitate cell volume control and contribute to many other physiological processes. Treatment with non-specific VRAC blockers or brain-specific deletion of the essential VRAC subunit LRRC8A
Mustafa Balkaya   +7 more
doaj  

Developing Predictive Molecular Maps of Human Disease through Community-based Modeling [PDF]

open access: yes, 2011
The failure of biology to identify the molecular causes of disease has led to disappointment in the rate of development of new medicines. By combining the power of community-based modeling with broad access to large datasets on a platform that promotes ...
Christine Suver   +10 more
core   +2 more sources

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