Results 61 to 70 of about 1,822,561 (192)

Circ-CIMIRC inhibition alleviates CIH-induced myocardial damage via FbxL4-mediated ubiquitination of PINK1

open access: yesiScience
Summary: Obstructive sleep apnea (OSA) is a common sleep disordered breathing diseases that characterized by chronic intermittent hypoxia (CIH). This work aimed to explore the role of circ-CIMIRC in CIH-induced myocardial injury.
Runhua Wu   +6 more
doaj  

The Contribution of lincRNAs at the Interface between Cell Cycle Regulation and Cell State Maintenance

open access: yesiScience, 2020
Summary: Cell cycle progression is controlled by the interplay of established cell cycle regulators. Changes in these regulators' activity underpin differences in cell cycle kinetics between cell types.
Adriano Biasini   +5 more
doaj  

Protocol for preparing monosodium urate crystals for in vitro and in vivo studies in mouse and human cells

open access: yesSTAR Protocols
Summary: Gout is caused by the deposition of monosodium urate crystals (MSUc) in the joints, triggering a unique inflammatory and metabolic response in macrophages.
Mohnish Alishala   +2 more
doaj  

Remodeling of the secretory pathway is coordinated with de novo membrane formation in budding yeast gametogenesis

open access: yesiScience
Summary: Gametogenesis in budding yeast involves a large-scale rearrangement of membrane traffic to allow the de novo formation of a membrane, called the prospore membrane (PSM). However, the mechanism underlying this event is not fully elucidated. Here,
Yasuyuki Suda   +5 more
doaj  

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