Results 141 to 150 of about 191,889 (301)

Biophysics: Concepts and Fields [PDF]

open access: yes
There is an idiom that “biophysicist is who discusses about biology when meets physicist, talks about physics when meets biologist and says joke when meets another biophysicist”. This idiom points to multidisciplinary nature of biophysics but what really
امانی, مجتبی
core  

Chemical Maturation Controls Bioavailability of Fetuin‐A‐Mineral Complexes in Biomineralization

open access: yesAdvanced Functional Materials, EarlyView.
The role of Fetuin‐A‐mineral complexes in matrix mineralization is unclear. Here, Fetuin‐A‐mineral complexes were found to exist in functionally distinct states that determine mineral bioavailability: chemically labile calciprotein monomers directly mineralize collagen fibrils, while chemically matured primary calciprotein particles require cellular ...
Judith M. Schaart   +8 more
wiley   +1 more source

Three‐Dimensional Biomimetic Aerogel Conduits with Electro‐Ionic‐Immune Coupling Reverse the Pathological Cascade of Spinal Cord Injury

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic aerogel conduit was engineered from a nanofiber of gelatin/poly(l‐lactic acid) doped with polypyrrole nanoparticles, integrated with tannic acid and Mg2+. This “electro‐ionic‐immune” strategy mimicked spinal cord properties, reduced calcium overload, inflammation, oxidative damage, promoted neural stem cell differentiation, suppressed ...
Qingxiang Liu   +9 more
wiley   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Nanofiber‐Supported Decellularized Matrix Membrane Creates a Biomimetic Biochemical and Biophysical Niche for Intestinal Organoid Epithelium

open access: yesAdvanced Healthcare Materials, EarlyView.
A nanofiber‐supported decellularized extracellular matrix (NaDE) membrane recreates key biochemical and mechanical features of native intestinal tissue. This platform enables the formation of a more physiologically relevant intestinal epithelium, enhancing stem cell maintenance and promoting diverse cell differentiation.
Jaeseung Youn   +7 more
wiley   +1 more source

Molecular Biophysics and Engineering Lab [PDF]

open access: yes
Molecular Biophysics sits at the crossroads of biology, chemistry, physics, and engineering—and is rapidly transforming how we understand life. Our lab focuses on the cytoskeletal machinery of the cell, aiming to uncover how molecular components work ...
University of Mississippi. School of Engineering
core  

Surprising features of nuclear receptor interaction networks revealed by live-cell single-molecule imaging

open access: yeseLife
Type II nuclear receptors (T2NRs) require heterodimerization with a common partner, the retinoid X receptor (RXR), to bind cognate DNA recognition sites in chromatin. Based on previous biochemical and overexpression studies, binding of T2NRs to chromatin
Liza Dahal   +5 more
doaj   +1 more source

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang   +7 more
wiley   +1 more source

Dissecting mechanisms of ligand binding and conformational changes in the glutamine-binding protein

open access: yeseLife
The glutamine-binding protein GlnBP is part of an ATP-binding cassette transporter system in Escherichia coli and uses two well-characterized conformational states, an open ligand-free and a closed-liganded state, to facilitate active amino-acid uptake ...
Zhongying Han   +17 more
doaj   +1 more source

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