Results 121 to 130 of about 318,972 (299)
Biophysics and Molecular Biology [PDF]
Nature, 1962 Molecular Biophysics By Richard B. Setlow and Ernest C. Pollard. (Addison-Wesley Series in the Life Sciences.) Pp. xiii + 545. (London: Pergamon Press, 1962.) 84s. net.
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Algorithmic Challenges in Computational Molecular Biophysics
Journal of Computational Physics, 1999 Computational techniques for modeling large biological molecules have emerged rapidly in recent years as an important complement to experiment. Computer-generated models and simulation data are essential for analyzing structural and kinetic details that are difficult to capture experimentally for large, floppy macromolecules in solution.
Schlick, Tamar +6 more
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Engineering of Glioblastoma‐Derived Biomimetic Vesicles and Their Structural and Molecular Features
Advanced Healthcare Materials, EarlyView.ABSTRACT Biomimetic nanosystems and vesicles have arisen as a novel approach to design vesicular transport systems with diverse therapeutic potential. The ‘biomimetic’ strategy involves the integration of cell membrane components into lipid bilayers, conferring them with biological properties originating from the cell of origin. Until now, most studies
Noelia Hernández‐Lobato +6 more
wiley +1 more source
New Insights into Vibrio cholerae Biofilms from Molecular Biophysics to Microbial Ecology. [PDF]
Adv Exp Med Biol, 2023 Tai JB, Ferrell MJ, Yan J, Waters CM.
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Advanced Healthcare Materials, EarlyView.Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang +7 more
wiley +1 more source
Molecular Biophysics of Class A G Protein Coupled Receptors-Lipids Interactome at a Glance-Highlights from the A2A Adenosine Receptor. [PDF]
Biomolecules, 2023 Tzortzini E, Kolocouris A.
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Advanced Healthcare Materials, EarlyView.Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal +7 more
wiley +1 more source
Engineered gene networks enable non-genetic drug resistance and enhanced cellular robustness
Engineering Biology, 2019 Drug resistance complicates the treatment of cancer and infectious diseases, and often arises from the elevated expression of a gene that neutralises or reduces drug activity.
Brendan Camellato +6 more
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Advanced Healthcare Materials, EarlyView.This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
Liquid-liquid phase separation of tau: From molecular biophysics to physiology and disease. [PDF]
Protein Sci, 2021 Rai SK +4 more
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