Results 111 to 120 of about 191,889 (301)

The Best Material from the VII Congress of Russian Biophysicists [PDF]

open access: yes
The purpose of this Special Issue is to demonstrate the current state of research in the field of biophysics in the Russian Federation [...
Anastasia A. Anashkina   +1 more
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Large-scale-free network organisation is likely key for biofilm phase transition

open access: yesEngineering Biology, 2019
Non-linear Kuramoto model has been used to study synchronised or sync behaviour in numerous fields; however, its application in biology is scarce. Here, the basic model has been introduced and examples where large-scale small-world or scale-free networks
Kumar Selvarajoo
doaj   +1 more source

Biophysics and Molecular Biology [PDF]

open access: yesNature, 1962
Molecular Biophysics By Richard B. Setlow and Ernest C. Pollard. (Addison-Wesley Series in the Life Sciences.) Pp. xiii + 545. (London: Pergamon Press, 1962.) 84s. net.
openaire   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

Biophysics [PDF]

open access: yes, 1999
The message of this book is that biophysics is the science of physical principles underlying the "phenomenon life" on all levels of organization. Rather than teaching "physics for biologists" or "physical methods applied to biology", it regards its ...
Glaser, Roland
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

Biophysics-Guided Lead Discovery of HBV Capsid Assembly Modifiers [PDF]

open access: yes
Hepatitis B virus (HBV) is the leading cause of chronic liver pathologies worldwide. HBV nucleocapsid, a key structural component, is formed through the self-assembly of the capsid protein units. Therefore, interfering with the self-assembly process is a
Zixing Fan (18291586)   +10 more
core   +1 more source

SYSTEMIC APPROACH TO TEACHING BIOPHYSICS TO STUDENTS OF MEDICAL INSTITUTIONS OF HIGHER EDUCATION

open access: yesНеперервна професійна освіта: теорія та практика
The theoretical part of the study analyzes the content of the principle of systematicity as a method of scientific research of complex systems, on the one hand, and as a principle of learning in combination with other didactic principles, on the other ...
Anatolii Yehorenkov
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

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