Results 111 to 120 of about 318,972 (299)

Cloud-based adaptive exon prediction for DNA analysis

open access: yesHealthcare Technology Letters, 2018
Cloud computing offers significant research and economic benefits to healthcare organisations. Cloud services provide a safe place for storing and managing large amounts of such sensitive data.
Srinivasareddy Putluri   +2 more
doaj   +1 more source

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

open access: yesAdvanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández   +14 more
wiley   +1 more source

SYSTEMIC APPROACH TO TEACHING BIOPHYSICS TO STUDENTS OF MEDICAL INSTITUTIONS OF HIGHER EDUCATION

open access: yesНеперервна професійна освіта: теорія та практика
The theoretical part of the study analyzes the content of the principle of systematicity as a method of scientific research of complex systems, on the one hand, and as a principle of learning in combination with other didactic principles, on the other ...
Anatolii Yehorenkov
doaj   +1 more source

Metabolic, Replication and Genomic Category of Systems in Biology, Bioinformatics and Medicine [PDF]

open access: yes, 2012
Metabolic-repair models, or (M,R)-systems were introduced in Relational Biology by Robert Rosen. Subsequently, Rosen represented such (M,R)-systems (or simply MRs)in terms of categories of sets, deliberately selected without any structure other than the ...
I. C. Baianu
core   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng   +16 more
wiley   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

open access: yesAdvanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa   +8 more
wiley   +1 more source

The molecular biophysics of extracellular vimentin and its role in pathogen-host interactions. [PDF]

open access: yesCurr Opin Cell Biol, 2023
Parvanian S   +3 more
europepmc   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

open access: yesAdvanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach   +4 more
wiley   +1 more source

Analytical approach for the calculation of promoter activities based on fluorescent protein expression data

open access: yesEngineering Biology, 2017
Characterisation of promoters, repressors, enhancers and so on, is not only essential for unravelling the inner workings of gene regulation, but also to enable the rational engineering of novel synthetic elements. Each putative regulatory region requires
Konstantinos Markakis   +2 more
doaj   +1 more source

Advanced Microscopy Techniques for Molecular Biophysics. [PDF]

open access: yesInt J Mol Sci, 2023
Barsanti L   +4 more
europepmc   +1 more source

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