Results 151 to 160 of about 147,841 (291)

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source

Amyloid inhibition by molecular chaperones in vitro can be translated to Alzheimer's pathology in vivo. [PDF]

RSC Med Chem, 2023
Abelein A, Johansson J.
europepmc   +1 more source

Mechanism of action of VP1-001 in cryAB(R120G)-associated and age-related cataracts [PDF]

, 2019
PurposeWe previously identified an oxysterol, VP1-001 (also known as compound 29), that partially restores the transparency of lenses with cataracts. To understand the mechanism of VP1-001, we tested the ability of its enantiomer, ent-VP1-001, to bind ...
Andley, Usha P., Covey, Douglas F., Dunyak, Bryan M., Gestwicki, Jason E., Hamilton, Paul D., Izrayelit, Yevgeniy, Makley, Leah N., McGlasson-Naumann, Brittney, Molnar, Kathleen S., Qian, Mingxing, Su, Bonnie   +10 more
core   +2 more sources

Molecular chaperones HSP40, HSP70, STIP1, and HSP90 are involved in stabilization of Cx43. [PDF]

Cytotechnology, 2023
An L, Gao H, Zhong Y, Liu Y, Cao Y, Yi J, Huang X, Wen C, Tong R, Pan Z, Yan X, Liu M, Wang S, Bai X, Wu H, Hu T.   +15 more
europepmc   +1 more source

Expression and characterisation of human glycerol kinase: the role of solubilising agents and molecular chaperones. [PDF]

Biosci Rep, 2023
Rani RM, Syngkli S, Nongkhlaw J, Das B.
europepmc   +1 more source

Molecular chaperone

Molecular chaperone
identifier:oai:t2r2.star.titech.ac.jp ...
openaire  

Reduction of Ribonucleotide Reductase Subunit RRM2 Potentially Impairs Gut Function of Woody Breast Broilers

Animal Research and One Health, EarlyView.
Woody breast compromises meat quality leading to reduced consumer appeal. Although its causes are unclear, improvements observed with certain dietary supplements suggest that gut health may influence woody breast development. Ribonucleotide reductase subunit RRM2 is vital for mitochondrial function and gastrointestinal integrity, and alteration in its ...
Majid Shakeri, Elizabeth Ziabtchenko, Janghan Choi, Caitlin E. Harris, Richard J. Buhr, Trevor R. Mitchell, Byungwhi Kong, Hong Zhuang, Brian Bowker   +8 more
wiley   +1 more source

Improved Production of Recombinant Carboxylesterase FumDM by Co-Expressing Molecular Chaperones in Pichia pastoris. [PDF]

Toxins (Basel), 2023
Jiang L, Guan X, Liu H, Chang X, Sun J, Sun C, Zhao C.   +6 more
europepmc   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Contribution of Extracellular Vesicles and Molecular Chaperones in Age-Related Neurodegenerative Disorders of the CNS. [PDF]

Int J Mol Sci, 2023
Noori L, Filip K, Nazmara Z, Mahakizadeh S, Hassanzadeh G, Caruso Bavisotto C, Bucchieri F, Marino Gammazza A, Cappello F, Wnuk M, Scalia F.   +10 more
europepmc   +1 more source