Results 161 to 170 of about 94,343 (283)

Contribution of Extracellular Vesicles and Molecular Chaperones in Age-Related Neurodegenerative Disorders of the CNS. [PDF]

Int J Mol Sci, 2023
Noori L, Filip K, Nazmara Z, Mahakizadeh S, Hassanzadeh G, Caruso Bavisotto C, Bucchieri F, Marino Gammazza A, Cappello F, Wnuk M, Scalia F.   +10 more
europepmc   +1 more source

A Solution for Exosome‐Based Analysis: Surface‐Enhanced Raman Spectroscopy and Artificial Intelligence

Advanced Intelligent Discovery, EarlyView.
Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz, Zakarya Al‐Shaebi, Omer Aydin   +2 more
wiley   +1 more source

The Impact of Hidden Structure on Aggregate Disassembly by Molecular Chaperones. [PDF]

Front Mol Biosci, 2022
Shoup D, Roth A, Puchalla J, Rye HS.
europepmc   +1 more source

Machine Learning‐Enhanced Random Matrix Theory Design for Human Immunodeficiency Virus Vaccine Development

Advanced Intelligent Discovery, EarlyView.
This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah, Muhammad Zulqarnain Zeb, Muhammad Husnain Zeb, Babar Shabbir   +3 more
wiley   +1 more source

Small heat shock proteins operate as molecular chaperones in the mitochondrial intermembrane space. [PDF]

Nat Cell Biol, 2023
Adriaenssens E, Asselbergh B, Rivera-Mejías P, Bervoets S, Vendredy L, De Winter V, Spaas K, de Rycke R, van Isterdael G, Impens F, Langer T, Timmerman V.   +11 more
europepmc   +1 more source

A Robust Deep Temporal Causal Discovery Platform for Single‐Cell Gene Regulatory Network Reconstruction

Advanced Intelligent Discovery, EarlyView.
scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta, Madison Dautle, Shaoqiang Zhang, Yong Chen   +3 more
wiley   +1 more source

Differential Interactions of Molecular Chaperones and Yeast Prions. [PDF]

J Fungi (Basel), 2022
Barbitoff YA, Matveenko AG, Zhouravleva GA.   +2 more
europepmc   +1 more source

Correction to "Model Peptides Enable Comparisons of Substrate Binding Modes of Hsp70 Molecular Chaperones". [PDF]

Biochemistry
Bhasne K, Dörries L, Maqtedar A, Mager ST, Clerico EM, Gierasch LM.   +5 more
europepmc   +1 more source

Model Peptides Enable Comparisons of Substrate Binding Modes of Hsp70 Molecular Chaperones. [PDF]

Biochemistry
Bhasne K, Dörries L, Maqtedar A, Mager ST, Clerico EM, Gierasch LM.   +5 more
europepmc   +1 more source

THE GENERAL CONCEPT OF MOLECULAR CHAPERONES [PDF]

This introductory article proposes a conceptual framework in which to consider the information that is emerging about the proteins called molecular chaperones, and suggests some definitions that may be useful in this new field of biochemistry.

core