Results 181 to 190 of about 146,944 (294)

A widespread family of molecular chaperones promotes the intracellular stability of type VIIb secretion system-exported toxins. [PDF]

Proc Natl Acad Sci U S A
Gkragkopoulou P, Garrett SR, Shah PY, Grebenc DW, Klein TA, Kim Y, Whitney JC.   +6 more
europepmc   +1 more source

Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes. [PDF]

Sci Adv, 2023
Sun Y, Papadaki GF, Devlin CA, Danon JN, Young MC, Winters TJ, Burslem GM, Procko E, Sgourakis NG.   +8 more
europepmc   +1 more source

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

International Journal of Cancer, EarlyView.
What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado, Angelica Macauda, Antonio José Cabrera‐Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz‐Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero‐Fernández, Elena Cabezudo, Fernando Reyes‐Zurita, Aaron D. Norman, Ramón García‐Sanz, Gabriele Capurso, Per Hoffmann, Ulrika Pettersson‐Kymmer, Francisco Jiménez‐Romera, S. Vincent Rajkumar, Niels Weinhold, Ludmila Vodickova, Christian Langer, Angelika Stein, Abdulkadir Karismaz, Victor Moreno, Markus M. Nöthen, Karl‐Heinz Jöckel, Francesca Tavano, Joaquín Martínez‐López, Shaji K. Kumar, Juan Francisco Gutiérrez‐Bautista, Daniela Basso, Florentin Späth, Yolanda Benavente, Michelle A. T. Hildebrandt, Börge Schmidt, Tereza Sevcikova, Rui Manuel Vieira Reis, Yang Li, Miguel Ángel López‐Nevot, Mihai G. Netea, Daniele Campa, Alyssa Clay‐Gilmour, Susan L Slager, Kari Hemminki, Celine M Vachon, Asta Försti, Federico Canzian, Juan Sainz   +54 more
wiley   +1 more source

Bacillus subtilis forms twisted cells with cell wall integrity defects upon removal of the molecular chaperones DnaK and trigger factor. [PDF]

Front Microbiol, 2022
Matavacas J, Hallgren J, von Wachenfeldt C.   +2 more
europepmc   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Developing nanobodies as allosteric molecular chaperones of glucocerebrosidase function. [PDF]

Nat Commun
Dal Maso T, Sinisgalli C, Zilio G, Franzin E, Tessari I, Pardon E, Steyaert J, Ballet S, Greggio E, Versées W, Plotegher N.   +10 more
europepmc   +1 more source

Molecular Chaperones in Osteosarcoma: Diagnosis and Therapeutic Issues. [PDF]

Cells, 2021
Lallier M, Marchandet L, Moukengue B, Charrier C, Baud'huin M, Verrecchia F, Ory B, Lamoureux F.   +7 more
europepmc   +1 more source

Achieving superior therapeutic effects on methicillin‐resistant Staphylococcus aureus infection via simple sulfonation process for preparing zwitterionic photosensitizer

Interdisciplinary Medicine, EarlyView.
The sulfonated zwitterionic photosensitizer (PYSO3) is synthesized by reacting maleic anhydride derivatives with 4‐aminopyridine to form PY, followed by sulfonation with 1,4‐butane sultone. It exhibits both photothermal and photodynamic properties, enabling effective eradication of MRSA and biofilms, as well as promoting wound healing in mice ...
Changxu Zhu, Yin Li, Qiyun Deng, Ruixin Guo, Yu Huang, Wenyan Guo, Xi Chen, Ben Zhong Tang, Zhiming Wang, Lidan Chen, Zhaohui Sun   +10 more
wiley   +1 more source

Molecular chaperones at the host-virus interface: heat shock protein roles in HIV-1 and emerging insights for HIV-2 and dual infection. [PDF]

Front Cell Infect Microbiol
Arthur SE, Klogo K, Mensah EK, Cudjoe MAP, Mensah AB, Ankrah NA, Omosule CL, Bonney EY, Kyei GB.   +8 more
europepmc   +1 more source

Molecular Chaperones and miRNAs in Epilepsy: Pathogenic Implications and Therapeutic Prospects. [PDF]

Int J Mol Sci, 2021
Zummo L, Vitale AM, Caruso Bavisotto C, De Curtis M, Garbelli R, Giallonardo AT, Di Bonaventura C, Fanella M, Conway de Macario E, Cappello F, Macario AJL, Marino Gammazza A.   +11 more
europepmc   +1 more source