Results 181 to 190 of about 4,011,919 (357)

The molecular chaperone GroEL in complex with denatured proteins: increasing stability against temperature and trypsin action

, 2018
Victor Marchenkov, Tatiana N. Melnik, Natalia Marchenko, Gennady V. Semisotnov   +3 more
openalex   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Neurotransmitters and molecular chaperones interactions in cerebral malaria: Is there a missing link? [PDF]

Front Mol Biosci, 2022
Daniyan MO, Fisusi FA, Adeoye OB.
europepmc   +1 more source

Does Environmentally Contingent Variation in the Level of Molecular Chaperones Mirror a Biochemical Adaptation to Abiotic Stress?

, 2011
Branka Tucić, Sanja Jovanović, Ana Vulet   +2 more
openalex   +2 more sources

The molecular chaperone CCT modulates the activity of the actin filament severing and capping protein gelsolin in vitro [PDF]

, 2015
Andreas Svanström, Julie Grantham
openalex   +1 more source

Mechanism of action of VP1-001 in cryAB(R120G)-associated and age-related cataracts [PDF]

, 2019
PurposeWe previously identified an oxysterol, VP1-001 (also known as compound 29), that partially restores the transparency of lenses with cataracts. To understand the mechanism of VP1-001, we tested the ability of its enantiomer, ent-VP1-001, to bind ...
Andley, Usha P., Covey, Douglas F., Dunyak, Bryan M., Gestwicki, Jason E., Hamilton, Paul D., Izrayelit, Yevgeniy, Makley, Leah N., McGlasson-Naumann, Brittney, Molnar, Kathleen S., Qian, Mingxing, Su, Bonnie   +10 more
core   +2 more sources

Cytokine‐Engineered Chimeric Antigen Receptor‐T Cell Therapy: How to Balance the Efficacy and Toxicity

Advanced Science, EarlyView.
Cytokine‐engineered CAR‐T cells represent a promising immunotherapy against malignancies due to direct tumor killing and potent immunity response. However, significant toxicities, including CRS and ICANS, have restricted clinical applications. How to keep the risk‐benefit balance of the advanced therapy is of great importance for maximizing the benefit
Xinru Zhang, Gulizeba Aimaiti, Yuanye Guan, Yuzhe Sha, Wei Zhou, Jiefeng Shen, Bo Zhao, Wei‐En Yuan   +7 more
wiley   +1 more source

Amyloid inhibition by molecular chaperones in vitro can be translated to Alzheimer's pathology in vivo. [PDF]

RSC Med Chem, 2023
Abelein A, Johansson J.
europepmc   +1 more source

Xaa-Arg-Gly Triplets in the Collagen Triple Helix Are Dominant Binding Sites for the Molecular Chaperone HSP47 [PDF]

, 2002
Takaki Koide, Yoshifumi Takahara, Shinichi Asada, Kazuhiro Nagata   +3 more
openalex   +1 more source

Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1 [PDF]

, 2020
Carlos Sànchez‐Martìn, Elisabetta Moroni, Mariarosaria Ferraro, Claudio Laquatra, Giuseppe Cannino, Ionica Masgras, Alessandro Negro, Paolo Quadrelli, Andrea Rasola, Giorgio Colombo   +9 more
openalex   +1 more source