Results 261 to 270 of about 5,665,898 (300)

Molecular Classification of Appendiceal Adenocarcinoma

Journal of Clinical Oncology, 2023
PURPOSE Appendiceal adenocarcinomas (ACs) are rare, histologically diverse malignancies treated as colorectal cancers despite having distinct biology and clinical behavior. To guide clinical decision making, we defined molecular subtypes of AC associated with patient survival, metastatic burden, and chemotherapy response.
Michael B. Foote, Henry Walch, Walid Chatila, Efsevia Vakiani, Chris Chandler, Felix Steinruecke, Garrett M. Nash, Zsofia Stadler, Sebastian Chung, Rona Yaeger, Maria Ignez Braghrioli, Jinru Shia, Yelena Kemel, Anna Maio, Margaret Sheehan, Benoit Rousseau, Guillem Argilés, Michael Berger, David Solit, Nikolaus Schultz, Luis A. Diaz, Andrea Cercek   +21 more
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Molecular classification and grading of meningioma

Journal of Neuro-Oncology, 2023
Join Dr. Randy D'Amico and Dr. Jason Sheehan of the Journal of Neuro-Oncology for a discussion with Dr. MacLean Nasrallah from the University of Pennsylvania Perelman School of Medicine and Dr. Kenneth Aldape from The National Cancer Institute's Center for Cancer Research for a discussion about their latest publication on the molecular classification ...
MacLean P. Nasrallah, Kenneth D. Aldape
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Molecular classification of living organisms

Journal of Molecular Evolution, 1995
Recent studies in molecular evolution have generated strong conflicts in opinion as to how world living organisms should be classified. The traditional classification of life into five kingdom has been challenged by the molecular analysis carried out mostly on rRNA sequences, which supported the division of the extant living organisms into three major ...
SACCONE C, GISSI, CARMELA, LANAVE C, PESOLE, Graziano   +3 more
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Molecular Classification of Breast Cancer

Surgical Pathology Clinics, 2012
This article reviews the conceptual and practical implications of the intrinsic subtype classification of breast cancers and the limitations of this approach. It presents the most extensively validated gene expression assays proposed as predictors of clinical outcome and discusses their potential clinical utility and limitations.
Jones, Robin Lewis, Constantinidou, Anastasia, Reis-Filho, J. S., Jones, Robin Lewis, Constantinidou, Anastasia, Reis-Filho, J. S.   +5 more
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Molecular Classification of Osteosarcoma

2009
Genomic technologies are now being used to identify new molecular markers or signatures for both diagnostic and prognostic purposes. Recently, we reported the molecular classification of pediatric osteosarcoma by expression profiling in an attempt to identify a signature that could predict the chemoresistance of a tumor before treatment is initiated ...
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Molecular classification of neoplasms of the pancreas

Human Pathology, 2009
The recent sequencing of the pancreatic cancer genome provides unprecedented insight into the fundamental nature of this deadly malignancy. Although much work still needs to be done, a molecular classification of neoplasms of the pancreas is emerging. Molecular genetics have been used to identify unique clinical subtypes of pancreatic cancer, to guide ...
Ralph H, Hruban, N Volkan, Adsay
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Toward a Molecular Classification of Melanoma

Journal of Clinical Oncology, 2007
The incidence of melanoma is increasing at one of the highest rates of any form of cancer in the United States, with the current lifetime risk being one in 68. At present, there are limited systemic therapies to treat advanced stages of melanoma, and the key to improved survival remains early detection.
Leslie A, Fecher, Staci D, Cummings, Megan J, Keefe, Rhoda M, Alani   +3 more
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Molecular Classification of Breast Cancer

PET Clinics, 2018
Breast cancer is a heterogeneous disease, observed traditionally by morphology and protein expression but, more recently with the advent of modern molecular technologies, at the genomic and transcriptomic level. This review describes the association between the different molecular subtypes with the histologic subtypes of breast cancer alongside some of
Elena, Provenzano, Gary A, Ulaner, Suet-Feung, Chin   +2 more
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Molecular Classification of Urothelial Carcinoma

Surgical Pathology Clinics
Urothelial carcinoma exhibits a wide spectrum of morphologic and molecular heterogeneity. Advances in molecular testing have improved our understanding of the molecular biology of urothelial carcinoma, including recurrent genomic alterations and transcriptomic features, leading to the development of molecular classification schemes with potential ...
Jie-Fu, Chen, Hikmat, Al-Ahmadie
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Lymphoma Classification: Morphology to Molecular

Journal of Investigative Medicine, 2020
An underlying theme in the history of medicine is progressive refinement in the understanding of disease and approaches to therapy guided by the evolution of technology applied to diagnosis. In hematology, with its origins in the application of microscopy to clinical diagnosis in the 19th century, this theme may be more readily visible than in other ...
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