Results 51 to 60 of about 224,084 (299)
Canadian Journal of Pain, 2023 Background Recent data suggest that restrictions related to COVID-19 resulted in changes in the prescribing patterns of opioids.Aims We sought to analyze Ontario health data for changes in frequencies among new and continuing users for the following ...
Alexandra Robins +6 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Quantum computing of molecular magnet Mn12 [PDF]
, 2002 Quantum computation in molecular magnets is studied by solving the time-dependent Schrödinger equation numerically. Following Leuenberger and Loss [Nature (London) 410, 789 (2001)], an external alternating magnetic field is applied to populate and ...
Zhou, B +7 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Molecular Computing: from conformational pattern recognition to complex processing networks [PDF]
, 1996 Natural biomolecular systems process information in a radically different manner than programmable machines. Conformational interactions, the basis of specificity and self-assembly, are of key importance.
Conrad, Michael, Zauner, Klaus-Peter
core
From prescriptive programming of solid-state devices to orchestrated self-organisation of informed matter [PDF]
, 2005 Achieving real-time response to complex, ambiguous, high-bandwidth data is impractical with conventional programming. Only the narrow class of compressible input-output maps can be specified with feasibly sized programs.
Zauner, Klaus-Peter, Klaus-Peter Zauner
core +1 more source
Bioinformatics Resource Manager: a systems biology web tool for microRNA and omics data integration
BMC Bioinformatics, 2019 Background The Bioinformatics Resource Manager (BRM) is a web-based tool developed to facilitate identifier conversion and data integration for Homo sapiens (human), Mus musculus (mouse), Rattus norvegicus (rat), Danio rerio (zebrafish), and Macaca ...
Joseph Brown +8 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Collaborative grid infrastructure for molecular simulations: The eMinerals minigrid as a prototype integrated computer and data grid [PDF]
, 2005 This paper describes a prototype grid infrastructure, called the eMinerals minigrid, for molecular simulation scientists. which is based on an integration of shared compute and data resources.
Allan, R. J. +46 more
core +1 more source