Results 51 to 60 of about 496,088 (311)

CircRNA May Not Be “Circular”

Frontiers in Genetics, 2021
Circular RNA (circRNA) is a novel regulatory non-coding RNA and participates in diverse physiological and pathological processes. However, the structures and molecular mechanisms of circRNAs remain unclear.
Handong Sun, Zijuan Wu, Zijuan Wu, Zijuan Wu, Ming Liu, Liang Yu, Liang Yu, Jianyong Li, Jianyong Li, Jianyong Li, Jinwen Zhang, Xiangming Ding, Hui Jin, Hui Jin, Hui Jin   +14 more
doaj   +1 more source

Conformation-dependent dynamics of macromolecular ions in the gas phase under an electrostatic field: A molecular dynamics simulation

, 2019
Highly charged macromolecular ions exhibit various conformations in gas. Intramolecular charge-to-charge interaction induces a transformation from a globular structure into a stretched one.
Yoshio Otani (710252), Hidenori Higashi (710247), Takaaki Orii (2739412), Mikio Kumita (710250), Tomoya Tamadate (6090473), Takafumi Seto (710251)   +5 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Tris(1H-benzimidazol-2-ylmethyl)amine methanol trisolvate

IUCrData, 2020
The structure of the tertiary amine tris(1H-benzimidazol-2-ylmethyl)amine (C24H21N7, abbreviated ntb) has been previously reported twice as solvates, namely the monohydrate and the acetonitrile–methanol–water (1/0.5/1.5) solvate, both with the tripodal ...
Bertin Anzaldo-Olivares, Maribel Arroyo, Armando Ramírez-Monroy, Sylvain Bernès   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Conformation Control of Iminodibenzyl-Based Thermally Activated Delayed Fluorescence Material by Tilted Face-to-Face Alignment With Optimal Distance (tFFO) Design

Frontiers in Chemistry, 2020
In organic light-emitting diodes (OLEDs), all triplet excitons can be harvested as light via reverse intersystem crossing (RISC) based on thermally activated delayed fluorescence (TADF) emitters. To realize efficient TADF, RISC should be fast.
Yu Kusakabe, Yoshimasa Wada, Hiromichi Nakagawa, Katsuyuki Shizu, Hironori Kaji   +4 more
doaj   +1 more source

Conformation-based Molecular Memories for Nanoscale MemComputing [PDF]

, 2023
We investigate the use of endohedral fullerenes and 6-(Ferrocenyl)hexanethiol cation as molecular non-volatile memory devices. We demonstrate stable encoding of the information in the geometry and dipole moment of these molecules. The write operation can
Graziano, Mariagrazia, Ardesi, Yuri, Spano, Chiara Elfi, Ardia, Gianmarco, Mo, Fabrizio, Piccinini, Gianluca   +5 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The crystal structure of (RS)-7-chloro-2-(2,5-dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one: two hydrogen bonds generate an elegant three-dimensional framework structure

Acta Crystallographica Section E: Crystallographic Communications, 2019
In the title compound, C61H15ClN2O3, the heterocyclic ring adopts an envelope conformation, folded across the N...N line, with the 2,5-dimethoxyphenyl unit occupying a quasi-axial site.
Kereyagalahally H. Narasimhamurthy, Chandra, Belakavadi K. Sagar, Kanchugarakoppal S. Rangappa, Hemmige S. Yathirajan, Christopher Glidewell   +5 more
doaj   +1 more source