Results 61 to 70 of about 1,982,601 (316)

Development of rapid, automated diagnostics for infectious disease: advances and challenges [PDF]

open access: yes, 2009
The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects.
Ince, J, McNally, A
core   +1 more source

Highly sensitive profiling somatic mutations of thyroid cancer by nucleotide-enrichment-based MALDI-TOF MS assay

open access: yesScientific Reports
Multiple mutation detection is increasingly essential for clinical applications targeting the diagnosis, treatment decision-making, and prognosis assessment of thyroid cancer, especially for the limited amount of thyroid fine-needle aspiration (FNA ...
Huili Bai   +7 more
doaj   +1 more source

Measurable Residual Disease Monitoring During Treatment for Pediatric Acute Myeloid Leukemia in First Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survival after relapse in pediatric acute myeloid leukemia (AML) remains poor, highlighting the critical importance of identifying prognostic factors to guide optimal relapse management. Methods We investigated the prognostic impact of multiparameter flow cytometry (MFC) measurable residual disease (MRD) in 188 patients with first ...
Camilla Poulsen   +21 more
wiley   +1 more source

Molecular Beacon for Detection miRNA-21 as a Biomarker of Lung Cancer [PDF]

open access: yes, 2022
UID/Multi/04349/ 2019 POCI-01-0145-FEDER-022122 ROTEIRO/0031/2013-PINFRA/22161/2016 LA/P/0140/2020Lung cancer (LC) is the leading cause of cancer-related death worldwide. Although the diagnosis and treatment of non-small cell lung cancer (NSCLC), which
Valente, Salete   +13 more
core   +1 more source

Epigenetic indicators of body mass predict survival outcomes in colorectal cancer patients: patient cohort analysis

open access: yesGenome Medicine
Background The prognostic relevance of body mass index (BMI) in colorectal cancer (CRC) remains controversial, partly due to disease-related weight loss.
Tanwei Yuan   +5 more
doaj   +1 more source

Comparison of Two Field Deployable PCR Platforms for SARS-CoV-2 and Influenza A and B Viruses’ Detection

open access: yesPathogens
Background: Respiratory viral infections are a major public health challenge and the most diagnosed medical condition, particularly for individuals living in close proximity, like military personnel.
Hakim Bouamar   +5 more
doaj   +1 more source

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver   +25 more
wiley   +1 more source

Plasmonic Mesoporous Composites as Molecular Sieves for SERS Detection [PDF]

open access: yes, 2013
Application of surface-enhanced Raman scattering (SERS) spectroscopy to the ultrasensitive analysis of small molecules in biological samples is complicated by signal contamination by ubiquitous macromolecules such as proteins, nucleic acids, or lipids ...
Angelome, Paula Cecilia   +9 more
core   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan   +18 more
wiley   +1 more source

Prediction of Biochemical Recurrence Based on Molecular Detection of Lymph Node Metastasis After Radical Prostatectomy. [PDF]

open access: yes, 2022
Background Molecular detection of lymph node (LN) micrometastases by analyzing mRNA expression of epithelial markers in prostate cancer (PC) patients provides higher sensitivity than histopathological examination.
Achim Fleischmann   +21 more
core   +1 more source

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