Results 91 to 100 of about 319,160 (295)
Parotid Gland Tumors: Molecular Diagnostic Approaches
Parotid gland pathology represents a web of differential diagnoses. There are many complex cases that require extensive diagnostic tests for a complete and correct final pathology diagnosis.
Crenguta Serboiu +9 more
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Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
The importance of molecular diagnostic techniques on evaluation of cancers
, 2023 Cancer is caused by genetic changes controlling cell progression and differentiation. These changes are unregulated when tumours advance and acquire invasive and metastatic capacities due to the innate biologic characteristics of the cancer cell. In vivo and in vitro models show that these molecular changes are crucial for tumour development and ...
Ajaykumar Chittipolu +2 more
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Development of rapid, automated diagnostics for infectious disease: advances and challenges
, 2009 The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects.
Ince, J, McNally, A
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Revista da Sociedade Brasileira de Medicina TropicalINTRODUCTION: Strongyloides stercoralis is an intestinal parasitic nematode that causes hyperinfection and/or a dissemination syndrome in hosts, which is often difficult to diagnose. This study aims to compare the diagnostic efficacy of four conventional
Laura Francisca Campo-Polanco +6 more
doaj +1 more source
Prognostic and predictive roles of microsatellite instability and mismatch repair deficiency in early-stage endometrial cancer: a structured narrative review [PDF]
Obstetrics & Gynecology ScienceThe incidence of endometrial cancer (EC) is rising, increasingly affecting younger women desiring fertility preservation. While the International Federation of Gynecology and Obstetrics staging system guides early-stage EC treatment, its prognostic and ...
Amirhossein Soleymani +3 more
doaj +1 more source
Identification of the Mycobacterium ulcerans protein MUL_3720 as a promising target for the development of a diagnostic test for Buruli ulcer [PDF]
, 2015 Buruli ulcer (BU) caused by Mycobacterium ulcerans is a devastating skin disease, occurring mainly in remote West African communities with poor access to health care.
Miriam Bolz +32 more
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular diagnostic techniques in cancer
, 2016 La transformació neoplàsica succeeix per l’acumulació consecutiva d’alteracions genètiques i epigenètiques que confereixen a les cèŀlules on ocorren avantatges selectius sobre les seves germanes, cosa
Perucho, Manuel +2 more
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