Results 81 to 90 of about 319,160 (295)

Molecular techniques for clinical diagnostic bacteriology

Turkish Bulletin of Hygiene and Experimental Biology, 2015
Moleküler yöntemler enfeksiyon hastalıkların patogenezinin ve epidemiyolojisinin anlaşılmasında çok önemli katkıda bulunmuştur. Polimeraz zincir reaksiyonu (PZR), en yaygın kullanılan hedef nükleik asit amplifikasyon yöntemidir. Bu yöntem ile tek bir nükleik asidin kopyası çok kısa bir süre içinde 107 kereden fazla çoğalır.
openaire   +3 more sources

The history of research on facioscapulohumeral muscular dystrophy

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Facioscapulohumeral muscular dystrophy (FSHD) is a common hereditary neuromuscular disease which is divided into FSHD1 and FSHD2. After years of research, FSHD has established complete molecular diagnostic methods, in which Southern blotting is commonly ...
Cheng ZHANG, Huan LI
doaj  

The application of intraoperative molecular diagnosis in glioma surgery

Chinese Journal of Contemporary Neurology and Neurosurgery
Background Glioma is the most common malignant tumor of the central nervous system, and intraoperative accurate diagnosis is critical for formulating rational surgical strategies.
HAN Zhe, LI Gang, XUE Hao
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Diagnostic Techniques: Serological and Molecular Approaches

, 2008
Virus laboratory diagnostics has an increasingly important role in modern patient care. Virological methods are needed to investigate the etiology of acute viral infection or the reactivation of a latent infection, as well as to follow virus load in antiviral treatments.
Vainionpää, R., Leinikki, P.
openaire   +1 more source

SEOM–SERAM–SEMNIM guidelines on the use of functional and molecular imaging techniques in advanced non-small-cell lung cancer [PDF]

, 2017
Imaging in oncology is an essential tool for patient management but its potential is being profoundly underutilized. Each of the techniques used in the diagnostic process also conveys functional information that can be relevant in treatment decision ...
Sánchez-Rovira, P. [0000-0003-2658-1467], García-Vicente, A.M., Delgado-Bolton, R.C. [0000-0002-8071-6513], Vilanova-Busquets, J.C. [0000-0003-2148-6751], Fierro-Alanis, M.P., Sánchez-Escribano, R. [0000-0002-5953-2867], Luna-Alcalá, A. [0000-0001-9358-3396], García-Figueiras, R., Fernández-Pérez, G., Ceballos-Viro, J., Alés-Martínez, J.E.   +10 more
core   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Reference materials (RMs) for analysis of the human factor II (prothrombin) gene G20210A mutation [PDF]

, 2005
The Scientific Committee of Molecular Biology Techniques (C-MbT) in Clinical Chemistry of the IFCC has initiated a joint project in co-operation with the European Commission, Joint Research Centre, Institute of Reference Materials and Measurements to ...
Tosetto, Alberto, Visvikis, Sophie, RIEGER Sandra, GANCBERG D, Kitchen, Steve, MARKI-ZAY Janos, MANNHALTER C., Schimmel, Heinz G., VISVIKIS S, Gancberg, David, CORBISIER P, REITSMA Pieter, KITCHEN S, TORDAI A, Rieger, Sandra, Halbmayer, Walter-Michael, REITSMA PH, SPANNAGL M, GANCBERG David, Tordai, Attilia, Opplinger Leibundgut, Elisabeth, SPANNAGL Michael, OPPLIGER LEIBUNDGUT E, NEUMAIER Michael, Oppliger Leibundgut, Elisabeth, MELEGH B, CORBISIER Philippe, OLDENBURG Johannes, RIEGER S, Corbisier, Philippe, OLDENBURG J, COOPER S, Leibundgut, Elisabeth Oppliger, HALBMAYER Walter-Michael, Cooper, Susan, HALBMAYER WM, COOPER Susan, KITCHEN Steve, MRKI ZAY J, Reitsma, Pieter H., Marki-Zay, János, Gemmati, Donato, TOSETTO A, VISVIKIS Sophie, TORDAI Attila, Melegh, Béla, Zadro, Renata, SCHIMMEL HG, Neumaier, Michael, KLEIN Christoph, SCHIMMEL Heinz, TOSETTO Alberto, Oldenburg, Johannes, MANNHALTER Christine, ZADRO R, Mannhalter, Christine, Klein, Christoph L., MELEGH Bela, NEUMAIER M, Spannagl, Michael, KLEIN CL, OPPLIGER LEIBUNDGUT Elisabeth, Cooper, S., GEMMATI Donato, ZADRO Renata   +64 more
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Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Current characteristics of tuberculosis and human immunodeficiency virus co-infection in a cohort of hospitalized patients in Medellín, Colombia

Biomédica: revista del Instituto Nacional de Salud, 2018
Introduction: Tuberculosis (TB) is an important cause of morbidity and mortality in HIV patients. It is unknown if the advent of molecular diagnostic methods and a greater availability of antiretroviral therapy (ART) in our country have changed some ...
Lina Ruiz, María Angélica Maya, Zulma Vanesa Rueda, Lucelly López, Lázaro Agustín Vélez   +4 more
doaj   +1 more source