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Molecular Diagnostic Techniques
2013Prior to the rapid development of molecular techniques for clinical diagnostics, cancer was evaluated mainly according to the traditional morphology under a microscope. The mapping of the human genome refreshes the way disease is diagnosed and treated, which is indeed a huge accomplishment in the field of medicine. With the emergence of novel molecular
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Techniques in Molecular Diagnostics
2016The book covers from the very basic introduction on molecular biology and diagnostics to the protocols of advanced assays that can be offered by a diagnostic laboratory. There is detailed description on the requirements for setting up a laboratory. The chapter on laboratory mathematics will help the reader in preparation of common laboratory solutions.
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Modern molecular cytogenetic techniques in genetic diagnostics
Trends in Molecular Medicine, 2002During the past decade, fluorescence in situ hybridization (FISH) has become an important complementing application in genetic diagnostics. The use of variable FISH techniques enhances the thorough interpretation of numerical and complex chromosome aberrations, bridging the gap between conventional chromosome banding analysis and molecular genetic DNA ...
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[Molecular diagnostic techniques of Wolbachia].
Yi chuan = Hereditas, 2005Wolbachia is a common and widespread group of bacteria found in reproductive tissues of arthropods. These bacteria are transmitted through the cytoplasm of eggs and have evolved various mechanisms for manipulating reproduction of their hosts. Because of important relationship with some major biological issues and implication of biological control and ...
Peng, Gong, Zuo-Rui, Shen
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Validation of molecular-diagnostic techniques in the parasitological laboratory
Veterinary Parasitology, 2006Diagnostic laboratories today often operate according to standard quality management procedures such as ISO/IEC 17025. This requires that only validated methods are used. Validation procedures help to document that a particular protocol used by the accredited laboratory has a guaranteed performance in that particular laboratory.
Franz J, Conraths, Gereon, Schares
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Molecular Diagnostic Techniques for the Clinical Evaluation of Gliomas
Diagnostic Molecular Pathology, 2005Newly developed molecular techniques have been integrated into the routine assessment of gliomas in some laboratories. These tests serve to complement the subjective nature of morphologic analysis. Such strategies add useful information regarding pathogenicity, patient survival, and potential response to treatment.
Todd W, Kelley +2 more
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Molecular Diagnostic Techniques for Onychomycosis: Validity and Potential Application
American Journal of Clinical Dermatology, 2017Diagnosis of onychomycosis requires positive findings by direct microscopy and fungal culture. Fungal culture is slow and difficult, with low yields. We compared two dermatophyte identification methods, one using a real-time polymerase chain reaction (PCR) method, and the other using fungal culture to validate the molecular method.Nail specimens were ...
Shinichi, Watanabe, Kazuya, Ishida
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Application of Molecular Diagnostic Techniques to Renal Epithelial Neoplasms
Clinics in Laboratory Medicine, 2005The application of molecular and cytogenetic techniques to the study of renal neoplasia has resulted in improved understanding of the biologic mechanisms that are responsible for tumor development and progression. It also revealed that several different and specific genetic events are responsible for tumorigenesis in the various categories and ...
Timothy D, Jones +2 more
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Molecular diagnostic techniques for use in response to bioterrorism
Expert Review of Molecular Diagnostics, 2003The use of micro-organisms as agents of biological warfare is considered inevitable for several reasons, including ease of production and dispersion, delayed onset of symptoms, ability to cause high rates of morbidity and mortality and difficulty in diagnosis.
Marcia A, Firmani, Larry A, Broussard
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Clinical Molecular Diagnostic Techniques: A Brief Review
2013The identification and characterization of the genetic basis of disease is often fundamental to diagnosis. Detection of pathogenic mutations in a DNA sample can lead to a diagnosis, possible prognosis, and prospective therapy treatments. Over the years, a variety of molecular biology techniques have been utilized in clinical diagnostic laboratories in ...
Megan L. Landsverk, Lee-Jun C. Wong
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