Development of rapid, automated diagnostics for infectious disease: advances and challenges [PDF]
The last 2 years has seen an exponential rise in the amount of research funding made available for the development of rapid diagnostic devices for infectious agents of medical importance. This review reports on several such projects.
Ince, J, McNally, A
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Acute febrile illness (AFI) is a morbid condition with a sudden onset of fever with at least seven days of evolution, where no signs or symptoms related to an apparent infection have been identified.
Ruth Cabrera +9 more
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Clinico-bacteriological Study and Molecular Detection of Campylobacter in Childhood Diarrhoea: A Cross-sectional Study [PDF]
Introduction: Campylobacter infections cause diarrhoeal diseases as frequently as Salmonella and Shigella infections. The prevalence of Campylobacter infection among children with acute diarrhoea in developing countries ranges from 5-35%.
Visakha Kadiyala +3 more
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Molecular Diagnostic Techniques for Malaria Infection - A Review
Malaria is the most threatening protozoal disease and a major health problem worldwide, especially in developing countries. WHO recommends that for every case of suspected malaria, a diagnostic test must be done to confirm the disease.
Yangora, Y. M., Usman, A. D.
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Assessment of the incorporation of CNV surveillance into gene panel next-generation sequencing testing for inherited retinal diseases. [PDF]
BACKGROUND: Diagnostic use of gene panel next-generation sequencing (NGS) techniques is commonplace for individuals with inherited retinal dystrophies (IRDs), a highly genetically heterogeneous group of disorders.
Arno, Gavin +14 more
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Gene expression analysis in microdissected renal tissue - Current challenges and strategies [PDF]
The architecture and compartmentalization of the kidney has stimulated the development of an array of microtechniques to study the functional differences between the distinct nephron segments. With the vast amounts of genomic sequence data now available,
Cohen, C. D., Kretzler, M.
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Marine nematode taxonomy in the DNA age: the present and future of molecular tools to access their biodiversity [PDF]
Molecular taxonomy is one of the most promising yet challenging fields of biology. Molecular markers such as nuclear and mitochondrial genes are being used in a variety of studies surveying marine nematode taxa.
da Silva, Maria Cristina +7 more
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Human ascariasis: diagnostics update [PDF]
Soil-transmitted helminths (STHs) infect over one billion people worldwide. Ascariasis may mimic a number of conditions, and individual clinical diagnosis often requires a thorough work-up.
Jourdan, Peter M., Lamberton, Poppy H.L.
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Use of a highly-sensitive rapid diagnostic test to screen for malaria in pregnancy in Indonesia
Background The sensitivity of rapid diagnostic tests (RDTs) for malaria is inadequate for detecting low-density, often asymptomatic infections, such as those that can occur when screening pregnant women for malaria.
Vera T. Unwin +11 more
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Background: Conventional blood cultures methods are associated with long turnaround times, preventing early treatment optimization in bloodstream infections.
Anna Maria Peri +5 more
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