Results 61 to 70 of about 7,339,385 (306)

Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning‐enabled molecular diagnostics

open access: yesEMBO Molecular Medicine, 2020
Limited therapy options due to antibiotic resistance underscore the need for optimization of current diagnostics. In some bacterial species, antimicrobial resistance can be unambiguously predicted based on their genome sequence.
A. Khaledi   +14 more
semanticscholar   +1 more source

Molecular diagnostics of periodontitis

open access: yesPostępy Higieny i Medycyny Doświadczalnej, 2017
The microorganisms that form dental plaque are the main cause of periodontitis. Their identification and the understanding of the complex relationships and interactions that involve these microorganisms, environmental factors and the host’s health status enable improvement in diagnostics and targeted therapy in patients with periodontitis. To this end,
Izabela, Korona-Głowniak   +4 more
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

The optimal vaccination strategy to control COVID-19: a modeling study in Wuhan City, China

open access: yesInfectious Diseases of Poverty, 2021
Background Reaching optimal vaccination rates is an essential public health strategy to control the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to simulate the optimal vaccination strategy to control the disease by developing an age ...
Ze-yu Zhao   +26 more
doaj   +1 more source

SARS-CoV-2 respiratory co-infections: Incidence of viral and bacterial co-pathogens

open access: yesInternational Journal of Infectious Diseases, 2021
The global coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in an unprecedented challenge to our healthcare system.
Vijay Singh   +3 more
doaj   +1 more source

Molecular Pathology of Skin Melanoma: Epidemiology, Differential Diagnostics, Prognosis and Therapy Prediction

open access: yesInternational Journal of Molecular Sciences, 2022
Similar to other malignancies, TCGA network efforts identified the detailed genomic picture of skin melanoma, laying down the basis of molecular classification.
J. Tímár, A. Ladányi
semanticscholar   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille   +9 more
wiley   +1 more source

Escherichia coli-derived virus-like particles in vaccine development

open access: yesnpj Vaccines, 2017
Recombinant virus-like particle-based vaccines are composed of viral structural proteins and mimic authentic native viruses but are devoid of viral genetic materials. They are the active components in highly safe and effective vaccines for the prevention
Xiaofen Huang   +4 more
doaj   +1 more source

Challenges and opportunities for the adoption of molecular diagnostics for anthelmintic resistance

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2020
Anthelmintic resistance is a significant threat to livestock production systems worldwide and is emerging as an important issue in companion animal parasite management.
A. Kotze   +3 more
semanticscholar   +1 more source

Molecular Diagnostics of ß-Thalassemia [PDF]

open access: yesBalkan Journal of Medical Genetics, 2012
ABSTRACT A high-quality hemoglobinopathy diagnosis is based on the results of a number of tests including assays for molecular identification of causative mutations. We describe the current diagnostic strategy for the identification of b-thalassemias and hemoglobin (Hb) variants at the International Reference Laboratory for Haemoglobinopathies ...
Plaseska-Karanfilska Dijana   +5 more
openaire   +3 more sources

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