Results 51 to 60 of about 7,339,385 (306)

Banff 2019 Meeting Report: Molecular diagnostics in solid organ transplantation–Consensus for the Banff Human Organ Transplant (B‐HOT) gene panel and open source multicenter validation

American Journal of Transplantation, 2020
This meeting report from the XV Banff conference describes the creation of a multiorgan transplant gene panel by the Banff Molecular Diagnostics Working Group (MDWG).
M. Mengel, A. Loupy, M. Haas, C. Roufosse, M. Naesens, E. Akalin, M. C. Clahsen‐van Groningen, J. Dagobert, A. Demetris, J. Duong van Huyen, Juliette Gueguen, F. Issa, B. Robin, I. Rosales, J. H. von der Thüsen, A. Sánchez‐Fueyo, R. Smith, Kathryn Wood, B. Adam, R. Colvin   +19 more
semanticscholar   +1 more source

Clinical applications of microarray-based diagnostic tests

BioTechniques, 2005
Nearly 15 years have passed since the possibility of analyzing nucleic acid analytes in a massively parallel fashion was proposed using the then new concept of microarrays.
Lin Wu, P. Mickey Williams, Walter H. Koch   +2 more
doaj   +1 more source

Correlation of TIMP1-MMP2/MMP9 Gene Expression Axis Changes with Treatment Efficacy and Survival of NSCLC Patients

Biomedicines, 2023
In the course of lung cancer, normal cells are transformed into cancerous ones, and changes occur in the microenvironment, including the extracellular matrix (ECM), which is not only a scaffold for cells, but also a reservoir of cytokines, chemokines and
Jacek Pietrzak, Agnieszka Wosiak, Dagmara Szmajda-Krygier, Rafał Świechowski, Mariusz Łochowski, Milena Pązik, Ewa Balcerczak   +6 more
doaj   +1 more source

Rapid Molecular Diagnostics in Vulvovaginal Candidosis

Diagnostics
Background/Objectives: Vulvovaginal candidosis (VVC) is a common condition among women, with current diagnostic methods relying on clinical evaluation and laboratory testing.
K. Akinosoglou, Georgios Schinas, Despoina Papageorgiou, Eleni Polyzou, Zoe Massie, S. Ozcelik, F. Donders, Gilbert G. G. Donders   +7 more
semanticscholar   +1 more source

Estimation of CYP3A4*1B single nucleotide polymorphism in patients with recurrent Major Depressive Disorder

Molecular Genetics & Genomic Medicine, 2019
Background Major depression is the most common mental illness in the world. Failures in treatment may occur due to the presence of a subtype of depression called TRD (Treatment‐ Resistant Depression).
Rafał Świechowski, Agnieszka Jeleń, Marek Mirowski, Monika Talarowska, Piotr Gałecki, Jacek Pietrzak, Damian Wodziński, Ewa Balcerczak   +7 more
doaj   +1 more source

An efficient isothermal PCR method for on-site detection of nucleic acid

BioTechniques, 2019
Convective PCR (CPCR) is an isothermal nucleic acid amplification technology; however, natural convection exhibits a chaotic and multiplex flow state, resulting in low amplification efficiency and specificity.
Shiyin Zhang, Jin Wang, Zhihao Zhuo, Xiaosong Su, Mengyuan Chen, Wendi Chen, Tingdong Li, Dongxu Zhang, Xiaoping Min, Shengxiang Ge, Ningshao Xia   +10 more
doaj   +1 more source

Pediatric low-grade glioma in the era of molecular diagnostics

Acta Neuropathologica Communications, 2020
Low grade gliomas are the most frequent brain tumors in children and encompass a spectrum of histologic entities which are currently assigned World Health Organisation grades I and II. They differ substantially from their adult counterparts in both their
S. Ryall, U. Tabori, C. Hawkins
semanticscholar   +1 more source

Molecular diagnostics in tuberculosis [PDF]

European Journal of Clinical Microbiology & Infectious Diseases, 2005
Molecular diagnostics in tuberculosis has enabled rapid detection of Mycobacterium tuberculosis complex in clinical specimens, identification of mycobacterial species, detection of drug resistance, and typing for epidemiological investigation. In the laboratory diagnosis of tuberculosis, the nucleic acid amplification (NAA) test is rapid and specific ...
Yuen, KY, Yew, WW, Cheng, VCC
openaire   +4 more sources

Long-read based de novo assembly of low-complexity metagenome samples results in finished genomes and reveals insights into strain diversity and an active phage system

BMC Microbiology, 2019
Background Complete and contiguous genome assemblies greatly improve the quality of subsequent systems-wide functional profiling studies and the ability to gain novel biological insights. While a de novo genome assembly of an isolated bacterial strain is
Vincent Somerville, Stefanie Lutz, Michael Schmid, Daniel Frei, Aline Moser, Stefan Irmler, Jürg E. Frey, Christian H. Ahrens   +7 more
doaj   +1 more source

Emergence of Ancylostoma caninum parasites with the benzimidazole resistance F167Y polymorphism in the US dog population

International Journal for Parasitology: Drugs and Drug Resistance, 2023
Background: Anthelmintic resistance to benzimidazole has been detected in the canine hookworm, Ancylostoma caninum. Benzimidazole resistance is believed to have developed originally in greyhounds, but has also been detected in non-greyhound pet dogs. The
Christian M. Leutenegger, Cecilia E. Lozoya, Jeffrey Tereski, Christian Savard, Jennifer Ogeer, Rene Lallier   +5 more
doaj   +1 more source