Results 31 to 40 of about 7,339,385 (306)

Regulation of Molecular Diagnostics

open access: yesAnnual Review of Genomics and Human Genetics, 2022
Molecular diagnostic tests enable rapid analysis of genomic and proteomic markers. These tests are subject to diverging premarket access and postmarket surveillance requirements and mechanisms in the United States and the European Union. Each of these jurisdictions has its own challenges in keeping the regulations up to date with technological ...
Gail H, Javitt, Erik R, Vollebregt
openaire   +2 more sources

Benefit of everolimus as a monotherapy for a refractory breast cancer patient bearing multiple genetic mutations in the PI3K/AKT/mTOR signaling pathway

open access: yesCancer Biology & Medicine, 2018
A postmenopausal patient with a diagnosis of estrogen receptor (ER) (+), progesterone receptor (PR) (+), and human epidermal growth factor receptor-2 (HER2) (-) breast cancer was reported.
Yehui Shi   +8 more
doaj   +1 more source

Toward Rapid and Accurate Molecular Diagnostics at Home

open access: yesAdvances in Materials, 2022
The global outbreaks of infectious diseases have significantly driven an imperative demand for rapid and accurate molecular diagnostics. Nucleic acid amplification tests (NAATs) feature high sensitivity and high specificity; however, the labor‐intensive ...
Wenpeng Liu, Luke P. Lee
semanticscholar   +1 more source

Molecular Diagnostics

open access: yesHematology, 2003
Abstract It is increasingly evident that molecular diagnostics, that is, the use of diagnostic testing to understand the molecular mechanisms of an individual patient’s disease, will be pivotal in the delivery of safe and effective therapy for many diseases in the future.
Rita M, Braziel   +7 more
openaire   +2 more sources

The potential of digital molecular diagnostics for infectious diseases in sub-Saharan Africa

open access: yesPLOS Digital Health, 2022
There is a large gap between diagnostic needs and diagnostic access across much of sub-Saharan Africa (SSA), particularly for infectious diseases that inflict a substantial burden of morbidity and mortality.
A. Cunnington
semanticscholar   +1 more source

Colorful Molecular Diagnostics [PDF]

open access: yesClinical Chemistry, 2012
Most diagnostic assays used daily in clinical laboratories are based on identifying and quantifying the presence of specific molecules that serve as markers of pathologic conditions and physiological status; however, these molecules are neither visualized nor counted directly.
Kapanidis, A, Crawford, R
openaire   +2 more sources

Current and Future Molecular Diagnostics of Tick-Borne Diseases in Cattle

open access: yesVeterinary Sciences, 2022
Ticks and tick-borne diseases such as babesiosis, anaplasmosis, ehrlichiosis, Lyme disease, Crimean Congo hemorrhagic fever, and Rocky Mountain spotted fever pose a significant threat to animal and human health.
K. Garcia, Mina Weakley, T. Do, S. Mir
semanticscholar   +1 more source

Molecular Diagnostic Techniques

open access: yesMedicine, 2001
Molecular diagnostic techniques will continue to transform clinical microbiology. They provide more rapid and sensitive testing that impacts directly on clinical management of infected patients. Molecular diagnostic tests arose from the need to detect micro-organisms that are slow or difficult to grow, or that are present in only small numbers. Nucleic
Fawley, Warren N, Wilcox, Mark H
openaire   +2 more sources

Comprehensive Analysis of the Expression and Clinical Significance of RAS Family Members in Non-Small Cell Lung Cancer Based on Bioinformatics Data and the A549 Cell Line Model

open access: yesApplied Sciences, 2022
Lung cancer is the second most frequent worldwide diagnosed cancer. Mutations in the RAS genes family are among the most common oncogenic alterations occurring in non-small cell lung cancer (NSCLC). Many treatment options against KRAS mutations have been
Milena Pązik   +4 more
doaj   +1 more source

Nanotechnology in Tumor Biomarker Detection: The Potential of Liganded Nanoclusters as Nonlinear Optical Contrast Agents for Molecular Diagnostics of Cancer

open access: yesCancers, 2021
Simple Summary The key factor in preventing premature death from cancer is an early and accurate diagnosis. While common diagnostic procedures are successful in the detection and rough description of a tumor mass, a deeper insight into cancer’s molecular
Guillaume F. Combes   +5 more
semanticscholar   +1 more source

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