Results 41 to 50 of about 424,818 (305)

Feasibility of controlling hepatitis E in Jiangsu Province, China: a modelling study

open access: yesInfectious Diseases of Poverty, 2021
Background Hepatitis E, an acute zoonotic disease caused by the hepatitis E virus (HEV), has a relatively high burden in developing countries. The current research model on hepatitis E mainly uses experimental animal models (such as pigs, chickens, and ...
Meng Yang   +24 more
doaj   +1 more source

Clinical applications of microarray-based diagnostic tests

open access: yesBioTechniques, 2005
Nearly 15 years have passed since the possibility of analyzing nucleic acid analytes in a massively parallel fashion was proposed using the then new concept of microarrays.
Lin Wu   +2 more
doaj   +1 more source

Advances in Molecular Diagnostics [PDF]

open access: yesBioMed Research International, 2013
People at present day are facing serious global challenges in healthcare from emerging and reemerging diseases. Research in molecular diagnostics has provided us with the better understanding of molecular processes affecting human health, and diseases and the tools derived thereof are becoming the standard of care for treatment of several diseases. The
Tavan Janvilisri   +2 more
openaire   +2 more sources

Malignant Catarrhal Fever: Understanding Molecular Diagnostics in Context of Epidemiology

open access: yes, 2011
Malignant catarrhal fever (MCF) is a frequently fatal disease, primarily of ruminants, caused by a group of gammaherpesviruses. Due to complexities of pathogenesis and epidemiology in various species, which are either clinically-susceptible or reservoir ...
Hong Li   +2 more
core   +1 more source

Osteoporosis: Molecular Pathology, Diagnostics, and Therapeutics

open access: yes, 2023
Osteoporosis is a major public health concern affecting millions of people worldwide and resulting in significant economic costs. The condition is characterized by changes in bone homeostasis, which lead to reduced bone mass, impaired bone quality, and ...
Babapelumi Adejuyigbe   +3 more
core   +1 more source

Correlation of TIMP1-MMP2/MMP9 Gene Expression Axis Changes with Treatment Efficacy and Survival of NSCLC Patients

open access: yesBiomedicines, 2023
In the course of lung cancer, normal cells are transformed into cancerous ones, and changes occur in the microenvironment, including the extracellular matrix (ECM), which is not only a scaffold for cells, but also a reservoir of cytokines, chemokines and
Jacek Pietrzak   +6 more
doaj   +1 more source

Molecular diagnostics in tuberculosis [PDF]

open access: yesEuropean Journal of Clinical Microbiology & Infectious Diseases, 2005
Molecular diagnostics in tuberculosis has enabled rapid detection of Mycobacterium tuberculosis complex in clinical specimens, identification of mycobacterial species, detection of drug resistance, and typing for epidemiological investigation. In the laboratory diagnosis of tuberculosis, the nucleic acid amplification (NAA) test is rapid and specific ...
Yuen, KY, Yew, WW, Cheng, VCC
openaire   +4 more sources

The Spectrum of Clinical Utilities in Molecular Pathology Testing Procedures for Inherited Conditions and Cancer: A Report of the Association for Molecular Pathology

open access: yes, 2016
Clinical utility describes the benefits of each laboratory test for that patient. Many stakeholders have adopted narrow definitions for the clinical utility of molecular testing as applied to targeted pharmacotherapy in oncology, regardless of the ...
Hagenkord, Jill   +17 more
core   +1 more source

Estimation of CYP3A4*1B single nucleotide polymorphism in patients with recurrent Major Depressive Disorder

open access: yesMolecular Genetics & Genomic Medicine, 2019
Background Major depression is the most common mental illness in the world. Failures in treatment may occur due to the presence of a subtype of depression called TRD (Treatment‐ Resistant Depression).
Rafał Świechowski   +7 more
doaj   +1 more source

An efficient isothermal PCR method for on-site detection of nucleic acid

open access: yesBioTechniques, 2019
Convective PCR (CPCR) is an isothermal nucleic acid amplification technology; however, natural convection exhibits a chaotic and multiplex flow state, resulting in low amplification efficiency and specificity.
Shiyin Zhang   +10 more
doaj   +1 more source

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