Results 41 to 50 of about 424,818 (305)
Feasibility of controlling hepatitis E in Jiangsu Province, China: a modelling study
Background Hepatitis E, an acute zoonotic disease caused by the hepatitis E virus (HEV), has a relatively high burden in developing countries. The current research model on hepatitis E mainly uses experimental animal models (such as pigs, chickens, and ...
Meng Yang +24 more
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Clinical applications of microarray-based diagnostic tests
Nearly 15 years have passed since the possibility of analyzing nucleic acid analytes in a massively parallel fashion was proposed using the then new concept of microarrays.
Lin Wu +2 more
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Advances in Molecular Diagnostics [PDF]
People at present day are facing serious global challenges in healthcare from emerging and reemerging diseases. Research in molecular diagnostics has provided us with the better understanding of molecular processes affecting human health, and diseases and the tools derived thereof are becoming the standard of care for treatment of several diseases. The
Tavan Janvilisri +2 more
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Malignant Catarrhal Fever: Understanding Molecular Diagnostics in Context of Epidemiology
Malignant catarrhal fever (MCF) is a frequently fatal disease, primarily of ruminants, caused by a group of gammaherpesviruses. Due to complexities of pathogenesis and epidemiology in various species, which are either clinically-susceptible or reservoir ...
Hong Li +2 more
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Osteoporosis: Molecular Pathology, Diagnostics, and Therapeutics
Osteoporosis is a major public health concern affecting millions of people worldwide and resulting in significant economic costs. The condition is characterized by changes in bone homeostasis, which lead to reduced bone mass, impaired bone quality, and ...
Babapelumi Adejuyigbe +3 more
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In the course of lung cancer, normal cells are transformed into cancerous ones, and changes occur in the microenvironment, including the extracellular matrix (ECM), which is not only a scaffold for cells, but also a reservoir of cytokines, chemokines and
Jacek Pietrzak +6 more
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Molecular diagnostics in tuberculosis [PDF]
Molecular diagnostics in tuberculosis has enabled rapid detection of Mycobacterium tuberculosis complex in clinical specimens, identification of mycobacterial species, detection of drug resistance, and typing for epidemiological investigation. In the laboratory diagnosis of tuberculosis, the nucleic acid amplification (NAA) test is rapid and specific ...
Yuen, KY, Yew, WW, Cheng, VCC
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Clinical utility describes the benefits of each laboratory test for that patient. Many stakeholders have adopted narrow definitions for the clinical utility of molecular testing as applied to targeted pharmacotherapy in oncology, regardless of the ...
Hagenkord, Jill +17 more
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Background Major depression is the most common mental illness in the world. Failures in treatment may occur due to the presence of a subtype of depression called TRD (Treatment‐ Resistant Depression).
Rafał Świechowski +7 more
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An efficient isothermal PCR method for on-site detection of nucleic acid
Convective PCR (CPCR) is an isothermal nucleic acid amplification technology; however, natural convection exhibits a chaotic and multiplex flow state, resulting in low amplification efficiency and specificity.
Shiyin Zhang +10 more
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