Results 21 to 30 of about 7,339,385 (306)

Evaluation of Alternative Transport Media for RT-qPCR-Based SARS-CoV-2 Testing

open access: yesInternational Journal of Analytical Chemistry, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), is still rapidly spreading as of March 2022. An accurate and rapid molecular diagnosis is essential to determine the exact number of confirmed
Young Hyun Baek   +8 more
doaj   +1 more source

Measurement of activity of developmental signal transduction pathways to quantify stem cell pluripotency and phenotypically characterize differentiated cells

open access: yesStem Cell Research, 2022
Important challenges in stem cell research and regenerative medicine are reliable assessment of pluripotency state and purity of differentiated cell populations.
Laurent Holtzer   +3 more
doaj   +1 more source

Recent Advances in Molecular Diagnostics of Fungal Plant Pathogens: A Mini Review

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Phytopathogenic fungal species can cause enormous losses in quantity and quality of crop yields and this is a major economic issue in the global agricultural sector. Precise and rapid detection and identification of plant infecting fungi are essential to
G. Hariharan, K. Prasannath
semanticscholar   +1 more source

Molecular diagnostic techniques [PDF]

open access: yesMedicine, 2009
Clinical microbiology laboratories increasingly rely on molecular diagnostic techniques. The various formats of nucleic acid amplification are the most frequently used molecular tests in the diagnosis of infectious diseases. In many clinical settings, polymerase chain reaction (PCR) is clearly the method of choice due to its exquisite sensitivity and ...
Kurkela, Satu, Brown, David W.G.
openaire   +2 more sources

Characterization of type-specific HPV prevalence in a population of persistent cutaneous warts in Flanders, Belgium

open access: yesScientific Reports, 2023
Cutaneous warts are benign skin lesions caused by the human papillomavirus (HPV). Even though they are considered benign, they can have a considerable impact on the quality of life and cause serious illness in certain immunocompromised populations ...
Nina Redzic   +6 more
doaj   +1 more source

Ultrafast and Real-Time Nanoplasmonic On-Chip Polymerase Chain Reaction for Rapid and Quantitative Molecular Diagnostics.

open access: yesACS Nano, 2021
Advent and fast spread of pandemic diseases draw worldwide attention to rapid, prompt, and accurate molecular diagnostics with technical development of ultrafast polymerase chain reaction (PCR). Microfluidic on-chip PCR platforms provide highly efficient
Byoung-Hoon Kang   +6 more
semanticscholar   +1 more source

Obtaining Reliable RT-qPCR Results in Molecular Diagnostics—MIQE Goals and Pitfalls for Transcriptional Biomarker Discovery

open access: yesLife, 2022
In this review, we discuss the development pipeline for transcriptional biomarkers in molecular diagnostics and stress the importance of a reliable gene transcript quantification strategy.
C. Grätz   +5 more
semanticscholar   +1 more source

High-Efficiency Plasma Separator Based on Immunocapture and Filtration

open access: yesMicromachines, 2020
The shortcomings of standard plasma-separation methods limit the point-of-care application of microfluidics in clinical facilities and at the patient’s bedside.
Xiaosong Su   +12 more
doaj   +1 more source

CRISPR Enzyme Kinetics for Molecular Diagnostics.

open access: yesAnalytical Chemistry, 2021
CRISPR-diagnostic assays have gained significant interest in the last few years. This interest has grown rapidly during the current COVID-19 pandemic, where CRISPR-diagnostics have been frontline contenders for rapid testing solutions.
A. Ramachandran, J. Santiago
semanticscholar   +1 more source

Long-read sequencing for molecular diagnostics in constitutional genetic disorders

open access: yesHuman Mutation, 2022
Long‐read sequencing (LRS) has been around for more than a decade, but widespread adoption of the technology has been slow due to the perceived high error rates and high sequencing cost.
L. Conlin   +4 more
semanticscholar   +1 more source

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