Results 1 to 10 of about 7,339,385 (306)
The importance of molecular diagnostics for infectious diseases in low-resource settings
Nature Reviews Microbiology, 2021 In settings with limited resources and a wide range of possible etiologies, molecular technologies offer an effective solution for infectious disease diagnostics, because they are agile, fast and flexible.
Iruka Okeke +2 more
exaly +2 more sources
CRISPR-Cas13a system: A novel tool for molecular diagnostics
Frontiers in Microbiology, 2022 The clustered regularly interspaced short palindromic repeats (CRISPR) system is a natural adaptive immune system of prokaryotes. The CRISPR-Cas system is currently divided into two classes and six types: types I, III, and IV in class 1 systems and types
Jintao Li, Li Jintao
exaly +2 more sources
International Journal of Molecular Sciences, 2020 Riboswitches and toehold switches are considered to have potential for implementation in various fields, i.e., biosensing, metabolic engineering, and molecular diagnostics.
TIN Hoang Trung Chau +2 more
exaly +2 more sources
Journal of the American Academy of Orthopaedic Surgeons, 2015 Orthopaedic infections are complex conditions that require immediate diagnosis and accurate identification of the causative organisms to facilitate appropriate management. Conventional methodologies for diagnosis of these infections sometimes lack accuracy or sufficient rapidity. Molecular diagnostics is an emerging area of bench-to-bedside research in
Hyonmin, Choe +4 more
+5 more sources
Beyond the WHO classification of meningioma: using molecular diagnostics to guide management
Advances in Clinical Neuroscience & Rehabilitation, 2023 Meningioma are the most common primary brain tumour. Classically, meningioma are phenotypically grouped using the World Health Organisation (WHO) classification system.
Abigail Clynch +9 more
doaj +1 more source
CRISPR-Cas Biochemistry and CRISPR-Based Molecular Diagnostics.
Angewandte Chemie, 2023 Polymerase chain reaction (PCR)-based nucleic acid testing has played a critical role in disease diagnostics, pathogen surveillance, and many more. However, this method requires a long turnaround time, expensive equipment, and trained personnel, limiting
Zhengyan Weng +7 more
semanticscholar +1 more source
Managing Viral Emerging Infectious Diseases via Current and Future Molecular Diagnostics
Diagnostics, 2023 Emerging viral infectious diseases have been a constant threat to global public health in recent times. In managing these diseases, molecular diagnostics has played a critical role. Molecular diagnostics involves the use of various technologies to detect
M. Altındiş +1 more
semanticscholar +1 more source
An update on current and novel molecular diagnostics for the diagnosis of invasive fungal infections
Expert Review of Molecular Diagnostics, 2023 Background Invasive fungal infections cause millions of infections annually, but diagnosis remains challenging. There is an increased need for low-cost, easy to use, highly sensitive and specific molecular assays that can differentiate between colonized ...
J. Jenks +8 more
semanticscholar +1 more source
BMC Cancer, 2021 Background The RAS family protooncogenes, including KRAS, NRAS and HRAS, encode proteins responsible for the regulation of growth, differentiation and survival of many cell types.
Milena Pązik +5 more
doaj +1 more source
Molecular diagnostics tailoring personalized cancer therapy—an oncologist’s view
Virchows Archiv, 2023 Medical oncology is rapidly evolving with the implementation of personalized, targeted therapies. Advances in molecular diagnostics and the biologic understanding of cancer pathophysiology led to the identification of specific genetic alterations as ...
J. Riedl +5 more
semanticscholar +1 more source