Results 11 to 20 of about 7,339,385 (306)

Detection of BRAF V600E in Fine-Needle Aspiration Samples of Thyroid Nodules by Droplet Digital PCR

International Journal of Endocrinology, 2022
Background. BRAF exon 15 p.V600E (BRAF V600E) mutation has been established as an important molecular marker for papillary thyroid carcinoma diagnosis by ultrasound-guided fine-needle aspiration biopsy (FNAB).
Sang-Yu Lu, Ying-Chao Chen, Jia-Lin Feng, Qin-Yi Zhou, Jing Chen, Chen-Fang Zhu, Miao-Miao Guo, Man-Man Zhang, Qian-Yue Zhang, Meng Lu, Liu Yang, Jing Wu, Shuang-Xia Zhao, Huai-Dong Song, Xiao-Ping Ye   +14 more
doaj   +1 more source

Assessment of the TGFB1 gene expression and methylation status of the promoter region in patients with colorectal cancer

Scientific Reports, 2022
The aim of this study was to evaluate the expression of the TGFB1 gene encoding the TGF-β1 cytokine in 64 patients, and then to compare it with clinico-pathological features.
Damian Wodziński, Agnieszka Wosiak, Jacek Pietrzak, Rafał Świechowski, Radzisław Kordek, Ewa Balcerczak   +5 more
doaj   +1 more source

Differential Expression of AP-2 Transcription Factors Family in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma—A Bioinformatics Study

Cells, 2023
Members of the activator protein 2 (AP-2) transcription factor (TF) family are known to play a role in both physiological processes and cancer development. The family comprises five DNA-binding proteins encoded by the TFAP2A to TFAP2E genes.
Dagmara Szmajda-Krygier, Adrian Krygier, Marta Żebrowska-Nawrocka, Jacek Pietrzak, Rafał Świechowski, Agnieszka Wosiak, Agnieszka Jeleń, Ewa Balcerczak   +7 more
doaj   +1 more source

Forty Years of Molecular Diagnostics for Infectious Diseases

Journal of Clinical Microbiology, 2022
Nearly 40 years have elapsed since the invention of the PCR, with its extremely sensitive and specific ability to detect nucleic acids via in vitro enzyme-mediated amplification.
Jonathan E. Schmitz, C. Stratton, D. Persing, Yi-Wei Tang   +3 more
semanticscholar   +1 more source

Molecular Diagnostics

Human Genomics, 2011
Cassiman Jean-Jacques
doaj   +2 more sources

Molecular Pathogenesis of Fibrosis, Thrombosis and Surfactant Dysfunction in the Lungs of Severe COVID-19 Patients

Biomolecules, 2022
The global scope and scale of the SARS-CoV-2 pandemic led to huge amounts of important data from clinical observations and experimental analyses being collected, in particular, regarding the long-term impact of COVID-19 on lung tissue. Visible changes in
Adrian Krygier, Dagmara Szmajda-Krygier, Rafał Świechowski, Jacek Pietrzak, Agnieszka Wosiak, Damian Wodziński, Ewa Balcerczak   +6 more
doaj   +1 more source

Microfluidics-based strategies for molecular diagnostics of infectious diseases

Military Medical Research, 2022
Traditional diagnostic strategies for infectious disease detection require benchtop instruments that are inappropriate for point-of-care testing (POCT). Emerging microfluidics, a highly miniaturized, automatic, and integrated technology, are a potential ...
Xin Wang, Xianzhe Hong, Yiwei Li, Ying Li, Jie Wang, Peng Chen, Bifeng Liu   +6 more
semanticscholar   +1 more source

miRNA in Molecular Diagnostics

Bioengineering, 2022
MicroRNAs are a class of small non-coding RNA molecules that regulate gene expression on post-transcriptional level. Their biogenesis consists of a complex series of sequential processes, and they regulate expression of many genes involved in all cellular processes. Their function is essential for maintaining the homeostasis of a single cell; therefore,
Maja Matulić, Paula Gršković, Andreja Petrović, Valerija Begić, Suzana Harabajsa, Petra Korać   +5 more
openaire   +3 more sources

Bioinformatics-Based Characterization of ATP-Binding Cassette Subfamily B Member 1 (ABCB1) Gene Expression in Non-Small-Cell Lung Cancer (NSCLC)

Applied Sciences, 2023
P-glycoprotein (P-gp) has been implicated in lung cancer development, disease progression, and patient survival. Changes in the ABCB1 expression level may correlate with tumorigenesis and the formation of multidrug resistance (MDR).
Agnieszka Maria Jeleń, Bartłomiej Strehl, Dagmara Szmajda-Krygier, Milena Pązik, Ewa Balcerczak   +4 more
doaj   +1 more source

Machine learning-augmented surface-enhanced spectroscopy toward next-generation molecular diagnostics

Nanoscale Advances, 2022
The world today is witnessing the significant role and huge demand for molecular detection and screening in healthcare and medical diagnosis, especially during the outbreak of COVID-19. Surface-enhanced spectroscopy techniques, including Surface-Enhanced
Hong Zhou, Liangge Xu, Zhihao Ren, Jiaqi Zhu, Chengkuo Lee   +4 more
semanticscholar   +1 more source