Results 121 to 130 of about 9,026,651 (342)
The evolution of the immune system of bees is defined by conservation, expansions, and losses
BMC BiologyBackground Insect pollinators, such as bees, provide essential ecosystem services yet face increasing environmental challenges, including pathogens, which can negatively impact host fitness.
Hongfei Xu +2 more
doaj +1 more source
The Origin and Evolution of Viruses as Molecular Organisms [PDF]
, 2009 Viruses are the most abundant life forms and the repertoire of viral genes is greater than that of cellular genes. It is also evident that viruses have played a major role in driving cellular evolution, and yet, viruses are not part of mainstream biology,
Claudiu I. Bandea
core +2 more sources
Molecular epidemiology, evolution and phylogeny of SARS coronavirus
Infection, Genetics and Evolution, 2019 Shortly after its emergence in southern China in 2002/2003, Severe Acute Respiratory Syndrome coronavirus (SARS-CoV) was confirmed to be the cause of SARS. Subsequently, SARS-related CoVs (SARSr-CoVs) were found in palm civets from live animal markets in
Hayes K. H. Luk +4 more
semanticscholar +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Communications BiologyMany plants are facultatively asexual, balancing short-term benefits with long-term costs of asexuality. During range expansion, natural selection likely influences the genetic controls of asexuality in these organisms.
Yangzi Wang +8 more
doaj +1 more source
Supernova Feedback in Molecular Clouds: Global Evolution and Dynamics
, 2016 We use magnetohydrodynamical simulations of converging warm neutral medium flows to analyse the formation and global evolution of magnetised and turbulent molecular clouds subject to supernova feedback from massive stars.
Banerjee, Robi +4 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Genetic Mechanism of Non-Targeted-Site Resistance to Diquat in Spirodela polyrhiza
PlantsUnderstanding non-target-site resistance (NTSR) to herbicides represents a pressing challenge as NTSR is widespread in many weeds. Using giant duckweed (Spirodela polyrhiza) as a model, we systematically investigated genetic and molecular mechanisms of ...
Martin Höfer +4 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Artificially Expanded Genetic Information Systems for New Aptamer Technologies
Biomedicines, 2018 Directed evolution was first applied to diverse libraries of DNA and RNA molecules a quarter century ago in the hope of gaining technology that would allow the creation of receptors, ligands, and catalysts on demand.
Elisa Biondi, Steven A. Benner
doaj +1 more source