Results 61 to 70 of about 9,026,651 (342)

Bacterial N4-methylcytosine as an epigenetic mark in eukaryotic DNA

Nature Communications, 2022
Eukaryotic DNA can be methylated as 5-methylcytosine and N6-methyladenine, but whether other forms of DNA methylation occur has been controversial. Here the authors show that a bacterial DNA methyltransferase was acquired >60 Mya in bdelloid rotifers ...
Fernando Rodriguez, Irina A. Yushenova, Daniel DiCorpo, Irina R. Arkhipova   +3 more
doaj   +1 more source

Evolutionary ecology of opsin gene sequence, expression and repertoire. [PDF]

, 2017
Linking molecular evolution to biological function is a long-standing challenge in evolutionary biology. Some of the best examples of this involve opsins, the genes that encode the molecular basis of light reception.
Owens, Gregory L, Rennison, Diana J
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

The Subcellular Proteome of a Planctomycetes Bacterium Shows That Newly Evolved Proteins Have Distinct Fractionation Patterns

Frontiers in Microbiology, 2021
The Planctomycetes bacteria have unique cell architectures with heavily invaginated membranes as confirmed by three-dimensional models reconstructed from FIB-SEM images of Tuwongella immobilis and Gemmata obscuriglobus.
Christian Seeger, Karl Dyrhage, Mayank Mahajan, Anna Odelgard, Sara Bergström Lind, Siv G. E. Andersson   +5 more
doaj   +1 more source

Analytical Biases Associated with GC-Content in Molecular Evolution

Frontiers in Genetics, 2017
Molecular evolution is being revolutionized by high-throughput sequencing allowing an increased amount of genome-wide data available for multiple species.
J. Romiguier, C. Roux
semanticscholar   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Evolutionary genomics of socially polymorphic populations of Pogonomyrmex californicus

BMC Biology
Background Social insects vary considerably in their social organization both between and within species. In the California harvester ant, Pogonomyrmex californicus (Buckley 1867), colonies are commonly founded and headed by a single queen (haplometrosis,
Mohammed Errbii, Ulrich R. Ernst, Aparna Lajmi, Eyal Privman, Jürgen Gadau, Lukas Schrader   +5 more
doaj   +1 more source

The SoftWipe tool and benchmark for assessing coding standards adherence of scientific software

Scientific Reports, 2021
Scientific software from all areas of scientific research is pivotal to obtaining novel insights. Yet the coding standards adherence of scientific software is rarely assessed, even though it might lead to incorrect scientific results in the worst case ...
Adrian Zapletal, Dimitri Höhler, Carsten Sinz, Alexandros Stamatakis   +3 more
doaj   +1 more source

Disk Growth in Bulge-Dominated Galaxies: Molecular Gas and Morphological Evolution

, 2007
Substantial numbers of morphologically regular early-type (elliptical and lenticular) galaxies contain molecular gas, and the quantities of gas are probably sufficient to explain recent estimates of the current level of star formation activity.
Alison Crocker, Francoise Combes, Lisa Young, Martin Bureau, Wiklind, Wiklind   +5 more
core   +1 more source

Evolution of an ancient protein function involved in organized multicellularity in animals. [PDF]

, 2016
To form and maintain organized tissues, multicellular organisms orient their mitotic spindles relative to neighboring cells. A molecular complex scaffolded by the GK protein-interaction domain (GKPID) mediates spindle orientation in diverse animal taxa ...
Anderson, Douglas P, Campodonico-Burnett, William, Hanson-Smith, Victor, King, Nicole, Prehoda, Kenneth E, Thornton, Joseph W, Volkman, Brian F, Whitney, Dustin S, Woznica, Arielle   +8 more
core   +2 more sources