Results 81 to 90 of about 49,991 (271)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

The biosafety of molecular farming in plants [PDF]

open access: yes, 2022
9 S.Molecular farming in plants provides an inexpensive and convenient way to produce biopharmaceutical molecules and other valuable proteins on a large scale.
Commandeur, U.   +2 more
core  

Design of a Type-1 Diabetes Vaccine Candidate Using Edible Plants Expressing a Major Autoantigen

open access: yesFrontiers in Plant Science, 2018
Type-1 diabetes (T1D) is a metabolic disease involving the autoimmune destruction of insulin-producing pancreatic beta cells. It is often diagnosed by the detection of autoantibodies, typically those recognizing insulin itself or the 65-kDa isoform of ...
Edoardo Bertini   +10 more
doaj   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

Pollen-mediated gene flow from transgenic safflower ( Carthamus tinctorius L.) intended for plant molecular farming to conventional safflower [PDF]

open access: yes, 2009
Field experiments were conducted in Chile and western Canada to measure short-distance (0 to 100 m) outcrossing from transgenic safflower (Carthamus tinctorius L.) intended for plant molecular farming to nontransgenic commodity safflower of the same ...
Christianson, Jed A.   +8 more
core   +2 more sources

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Molecular farming of medicines: a field of growing promise [PDF]

open access: yes, 2001
Man has been using plants as a source of medicines for millennia. From the earliest stages of civilization, herbs and plant extracts have been sought that ease suffering and cure disease.
Schillberg, Stefan Johannes   +6 more
core   +1 more source

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

open access: yesAdvanced Engineering Materials, EarlyView.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele   +2 more
wiley   +1 more source

From Farming to "Pharming". Risks and Policy Challenges of Third Generation GM Crops [PDF]

open access: yes
Commercial and academic activities in the production of pharmaceuticals or other substances of industrial interests from genetically modified plants, i.e. molecular farming, have so far centred in the USA and Canada. Recent increases in EU activities and
Armin Spörk
core  

Sustainability and traceability in marine cultured pearl production [PDF]

open access: yes, 2014
For centuries, wild pearl oysters and mussels were fished in the quest for natural pearls and shell material. This eventually led to the drastic overexploitation of oyster stocks in many areas of the globe.
Cartier, Laurent Emmanuel Henri
core   +1 more source

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