Results 41 to 50 of about 3,395,940 (292)

A Fluorogenic Biosensor for Direct Detection of Vibrio vulnificus, a Climate Change Biomarker

open access: yesMicrobiologyOpen
Vibrio vulnificus, a marine pathogen and climate change biomarker, poses serious risks to human and animal health through seafood consumption and seawater exposure. Rapid detection methods are urgently needed for both vibriosis diagnosis and surveillance
M. Nieves Aranda   +8 more
doaj   +1 more source

A modular design of molecular qubits to implement universal quantum gates

open access: yesNature Communications, 2016
The physical implementation of quantum information processing requires individual qubits and entangling gates. Here, the authors demonstrate a modular implementation through chemistry, assembling molecular {Cr7Ni} rings acting as qubits, with ...
Jesús Ferrando-Soria   +11 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Understanding the Molecular Gates of KirBac3.1 [PDF]

open access: yesBiophysical Journal, 2013
Potassium currents across cell membranes are an essential part of electrical signalling in all cells. KirBac channels are prokaryotic homologs to mammalian Kir channels and superposition of the recently solved structures show that the fold and key features are almost indistinguishable. Potassium currents are proposed to be switched on and off using two
El-Ajouz, Sam   +3 more
openaire   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Tracing a new path in the field of AI and robotics: mimicking human intelligence through chemistry. Part I: molecular and supramolecular chemistry

open access: yesFrontiers in Robotics and AI, 2023
Chemical Artificial Intelligence (CAI) is a brand-new research line that exploits molecular, supramolecular, and systems chemistry in wetware (i.e., in fluid solutions) to imitate some performances of human intelligence and promote unconventional ...
Pier Luigi Gentili, Pasquale Stano
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Gates Notice of Adopted Amendment (2009-08-05)

open access: yes, 2009
6 pp. Adopted 2009-08-05. Department of Land Conservation and Development Notice of Adopted AmendmentThe City of Gates amended portion of its comprehensive plan sections of which had not be updated since 1978.
Gates
core   +1 more source

Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling

open access: yesNature Communications, 2019
Potassium channels such as MthK are presumed to have two allosterically coupled gates, the activation gate and the selectivity filter gate, that control gating transitions. Here authors use X-ray crystallography and molecular dynamics simulations on MthK
Wojciech Kopec   +2 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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