Results 31 to 40 of about 1,535,544 (371)
iScience, 2023 Summary: Ionizing radiation (IR) is a risk factor for acute myeloid leukemia (rAML). Murine rAMLs feature both hemizygous chromosome 2 deletions (Del2) and point mutations (R235) within the hematopoietic regulatory gene Spi1.
Natalie Brown +9 more
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Chloroplast microsatellites: measures of genetic diversity and the effect of homoplasy [PDF]
Molecular Ecology 14, 5 (2005) 1333-41, 2009 Chloroplast microsatellites have been widely used in population genetic studies of conifers in recent years. However, their haplotype configurations suggest that they could have high levels of homoplasy, thus limiting the power of these molecular markers.
arxiv +1 more source
Regulation of gene expression and its role in long-term memory and synaptic plasticity [PDF]
, 1997 Histories of science yet to be written will view the latter half of this century as the Age of Molecular Genetics. From a flash of insight that yielded the double helix (1) to the first genetic clone of a mammal (2), molecular genetics has invaded every ...
Tully, T.
core +2 more sources
The molecular genetics and cellular mechanisms underlying pulmonary arterial hypertension [PDF]
, 2012 Pulmonary arterial hypertension (PAH) is an incurable disorder clinically characterised by a sustained elevation of mean arterial pressure in the absence of systemic involvement.
Machado, Rajiv
core +2 more sources
Genetic Aspect of Headache [PDF]
, 2017 Headache is a multifactorial disease and the genetic basis is not clear yet. We review recent findings about molecular basis of subtypes of headache. The fundamentals of molecular genetics and the recent advances in this area are important for clinicians
Edgünlü, Tuba Gökdoğan +1 more
core +2 more sources
Interrogating cell type-specific cooperation of transcriptional regulators in 3D chromatin
iScience, 2021 Summary: Context-specific activities of transcription regulators (TRs) in the nucleus modulate spatiotemporal gene expression precisely. Using the largest ChIP-seq data and chromatin loops in the human K562 cell line, we initially interrogated TR ...
Xianfu Yi +15 more
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Stochastic Synchronization of Genetic Oscillator Networks [PDF]
BMC Systems Biology, Vol.1, article no.6, 2007, 2007 The study of synchronization among genetic oscillators is essential for the understanding of the rhythmic phenomena of living organisms at both molecular and cellular levels. Genetic networks are intrinsically noisy due to natural random intra- and inter-cellular fluctuations. Therefore, it is important to study the effects of noise perturbation on the
arxiv +1 more source
Advance of molecular marker application in the tobacco research [PDF]
, 2010 Tobacco (Nicotiana spp.) is one of the most important commercial crops in the world. During the last two decades, molecular markers have entered the scene of genetic improvement in different fields of agricultural research.
Liu, XZ, Zhang, HY
core +2 more sources
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Sex-biased genome-editing effects of CRISPR-Cas9 across cancer cells dependent on p53 status
iScience, 2023 Summary: The CRISPR-Cas9 system has emerged as the dominant technology for gene editing and clinical applications. One major concern is its off-target effect after the introduction of exogenous CRISPR-Cas9 into cells.
Mengbiao Guo, Yuanyan Xiong
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