Results 41 to 50 of about 833,805 (164)

Molecular Genetics of Gastric Adenocarcinoma

Proceedings of Singapore Healthcare, 2010
Gastric carcinoma is the second leading cause of cancer deaths in the world. Its aetiology is closely linked to the bacterial pathogen Helicobacter pylori which is believed to induce a state of chronic inflammation that predisposes to a cascade of ...
Alvin Kim Hock Eng MMed (Surgery), FRCSEd, Oi Lian Kon FRCPC, MD   +1 more
doaj   +1 more source

Molecular genetics of suicide

Zdravniški Vestnik, 2006
Background: Suicide is a complex phenomenon that is triggered by environmental factors, and probably partially also by genetic code. Genetic studies performed on suicide brain contributed interesting findings on serotonergic, dopaminergic and ...
Alja Videtič, Galina Pungerčič
doaj  

Molecular Genetics of Stroke

Siriraj Medical Journal, 2008
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Manop Pithukpakorn
doaj  

PPM1G promotes cell proliferation via modulating mutant GOF p53 protein expression in hepatocellular carcinoma

iScience
Summary: The serine/threonine protein phosphatase family involves series of cellular processes, such as pre-mRNA splicing. The function of one of its members, protein phosphatase, Mg2+/Mn2+ dependent 1G (PPM1G), remains unclear in hepatocellular ...
Wen Hu, Shao-Lin Ma, Liang Qiong, Yu Du, Li-Ping Gong, Yu-Hang Pan, Li-Ping Sun, Jing-Yun Wen, Jian-Ning Chen, Xin-Yuan Guan, Chun-Kui Shao   +10 more
doaj   +1 more source

Molecular genetics of cataract.

Indian Journal of Ophthalmology, 2000
Studies on hereditary congenital cataracts have led to the identification of genes involved in formation of these cataracts. Knowledge of the structure and function of a particular gene and the effect of disease-associated mutations on its function are ...
Kannabiran Chitra, Balasubramanian D.
doaj  

Assessing structure-function impacts on Vitellogenin by leveraging allelic variant found in honey bee subspecies Apis mellifera mellifera

iScience
Summary: Advances involving artificial intelligence (AI) and experimental structure determination can provide detailed pictures of complex protein structures and their variations.
Vilde Leipart, Oriol Gracia Carmona, Christine Orengo, Franca Fraternali, Gro V. Amdam   +4 more
doaj   +1 more source

Simple and highly specific targeting of resident microglia with adeno-associated virus

iScience
Summary: Microglia, as the immune cells of the central nervous system (CNS), play dynamic roles in both healthy and diseased conditions. The ability to genetically target microglia using viruses is crucial for understanding their functions and advancing ...
Carolina Serrano, Sergio Cananzi, Tianjin Shen, Lei-Lei Wang, Chun-Li Zhang   +4 more
doaj   +1 more source

MOLECULAR GENETICS FUNDAMENTALS AND WOMEN DISEASES GENЕTIC RISK FACTORS

Медицинский вестник Юга России, 2016
Exponential data quantity growth in the field of molecular genetics and genetic terminology growing list can easily confuse the doctor who doesn’t have special preparation.
E. A. Maylyan, D. E. Maylyan
doaj   +1 more source

The Autism-Related Protein SETD5 Controls Neural Cell Proliferation through Epigenetic Regulation of rDNA Expression

iScience, 2020
Summary: Haploinsufficiency of SETD5 is implicated in syndromic autism spectrum disorder (ASD), but the molecular mechanism underlying the pathological role of this protein has remained unclear.
Tadashi Nakagawa, Satoko Hattori, Risa Nobuta, Ryuichi Kimura, Makiko Nakagawa, Masaki Matsumoto, Yuko Nagasawa, Ryo Funayama, Tsuyoshi Miyakawa, Toshifumi Inada, Noriko Osumi, Keiichi I. Nakayama, Keiko Nakayama   +12 more
doaj   +1 more source

Molecular Genetics of Cataract [PDF]

, 2015
Lens opacities or cataract(s) represent a universally important cause of visual impairment and blindness. Typically, cataract is acquired with aging as a complex disorder involving environmental and genetic risk factors. Cataract may also be inherited with an early onset either in association with other ocular and/or systemic abnormalities or as an ...
Alan, Shiels, J Fielding, Hejtmancik
openaire   +2 more sources