Results 61 to 70 of about 1,566,823 (304)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Molecular Genetics of Gastric Adenocarcinoma

Proceedings of Singapore Healthcare, 2010
Gastric carcinoma is the second leading cause of cancer deaths in the world. Its aetiology is closely linked to the bacterial pathogen Helicobacter pylori which is believed to induce a state of chronic inflammation that predisposes to a cascade of ...
Alvin Kim Hock Eng MMed (Surgery), FRCSEd, Oi Lian Kon FRCPC, MD   +1 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Molecular genetics of suicide

Zdravniški Vestnik, 2006
Background: Suicide is a complex phenomenon that is triggered by environmental factors, and probably partially also by genetic code. Genetic studies performed on suicide brain contributed interesting findings on serotonergic, dopaminergic and ...
Alja Videtič, Galina Pungerčič
doaj  

Gene expression drives the evolution of dominance. [PDF]

, 2018
Dominance is a fundamental concept in molecular genetics and has implications for understanding patterns of genetic variation, evolution, and complex traits.
A Durvasula, A Platt, AF Agrawal, B Charlesworth, BM Henn, BY Kim, CD Huber, CD Huber, D Enard, D Ortega-Del Vecchyo, D Szklarczyk, DJ Balick, F Gao, F Manna, FH Shaw, H Kacser, HA Orr, I Frumkin, J Yang, JBS Haldane, JS Sanjak, KE Lohmueller, KM Teshima, LD Hurst, MA DePristo, MJ Simmons, N Phadnis, P Cingolani, P Lamesch, PY Novikova, RA Fisher, RD Hernandez, RN Gutenkunst, S Glémin, S Ossowski, S Williamson, S Wright, SH Williamson, T Bedford, T Kawakatsu, T Mukai, TI Gossmann, TT Hu, X Zheng, YB Simons   +44 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Molecular Genetics of Stroke

Siriraj Medical Journal, 2008
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Manop Pithukpakorn
doaj  

PPM1G promotes cell proliferation via modulating mutant GOF p53 protein expression in hepatocellular carcinoma

iScience
Summary: The serine/threonine protein phosphatase family involves series of cellular processes, such as pre-mRNA splicing. The function of one of its members, protein phosphatase, Mg2+/Mn2+ dependent 1G (PPM1G), remains unclear in hepatocellular ...
Wen Hu, Shao-Lin Ma, Liang Qiong, Yu Du, Li-Ping Gong, Yu-Hang Pan, Li-Ping Sun, Jing-Yun Wen, Jian-Ning Chen, Xin-Yuan Guan, Chun-Kui Shao   +10 more
doaj   +1 more source

Metagenomics for Bacteriology [PDF]

, 2015
The study of bacteria, or bacteriology, has gone through transformative waves since its inception in the 1600s. It all started by the visualization of bacteria using light microscopy by Antonie van Leeuwenhoek, when he first described “animalcules ...
del Castillo, Erika, Izard, Jacques
core   +1 more source