Results 91 to 100 of about 3,265,759 (283)

Structure‐Guided Balancing of Ambipolar Transport Enables Symmetric Switching in Heterojunction Bilayer Organic Transistor Inverters

Advanced Functional Materials, EarlyView.
Balancing the spatially separated p‐ and n‐type transport pathways in heterojunction‐bilayer OTFTs enables symmetric inverter switching (VM ≈ 0.5VDD), whereas discrete integration of unipolar OTFTs gives polarity‐dependent and resistive responses. ABSTRACT High inverter performance in ambipolar organic electronics requires balanced channel strengths ...
Sohyun Choi, Young Yong Kim, Ji Ho Youk, Hoichang Yang   +3 more
wiley   +1 more source

glue-viz/glue: v1.20.0

<p><!-- Release notes generated using configuration in .github/release.yml at main --></p> <h2>What's Changed</h2> <h3>New Features</h3> <ul> <li>Allow transparent regions in composite images when out
Jon Carifio, Chris Beaumont, Thomas Robitaille, Simon Conseil, Yuval Langer, Maarten Breddels, Nabil Freij, Dan D'Avella, Samuel Bennett, Peter Teuben, ejeschke, Robin Wilson, Brigitta Sipőcz, Jonathan Foster, P. L. Lim, Stuart Mumford, Adam Ginsburg, Brett M. Morris, Jonathan Eisenhamer, Derek Homeier, specmicp, Robel Geda, Jeffrey SubbaRao, Will Dampier, Adrian Price-Whelan, Kyle Conroy, Clément Robert, Jesse Averbukh, Ricky O'Steen, John ZuHone   +29 more
core   +1 more source

Sacrificial‐Layer‐Assisted Heat‐Affected‐Zone Suppression in Laser Patterning of PET for High‐Performance Flexible Devices

Advanced Functional Materials, EarlyView.
A removable sacrificial polymer layer engineers the thermal boundary condition during nanosecond laser ablation of PET, suppressing heat‐affected‐zone formation without relying on costly ultrafast lasers. This strategy enables deep, high‐aspect‐ratio trenches with no detectable heat‐affected zone, templating silver‐filled mesh electrodes with record ...
Mehdi Zarei, Mirza Sahaluddin, Mostafa Bedewy, Paul W. Leu   +3 more
wiley   +1 more source

PROTACs and Glues: Striking Perspectives for Engineering Cancer Therapy À La Carte

Pharmaceuticals
PROTACs are bifunctional small molecules that simultaneously bind a target protein and a component of the ubiquitin–proteasome system, thereby inducing selective degradation of the target.
Jean-Marc Ferrero, Jocelyn Gal, Baharia Mograbi, Gérard Milano   +3 more
doaj   +1 more source

Structure‐Property Relationships in Catecholamine Coatings for Broad Surface Functionalization

Advanced Functional Materials, EarlyView.
Inspired by mussel adhesive proteins (MAPs), six catecholamine molecules with different molecular structure were systematically characterized and compared based on their ability to form homogeneous, reactive coatings. Highlighting candidates capable of balancing coating properties of interest, their successful use as primer layers for organic and ...
Caroline F. Harms, Qiming Li, Ye‐Sol Kim, Anish Tuteja, Jinsang Kim, Abdon Pena‐Francesch   +5 more
wiley   +1 more source

A dual-mode molecular glue for precision control of plant hormone co-receptor interactions in rice

Cell Reports Physical Science
Summary: Molecular glue degraders (MGDs) offer a powerful modality for modulating protein-protein interactions. In plants, (3R, 7S)-jasmonoyl-L-isoleucine (JA-Ile) acts as a natural MGD by recruiting JAZ repressors to the E3 ubiquitin ligase subunit COI1
Taichi Okumura, Kotaro Matsumoto, Koji Miyamoto, Takao Nomura, Kairi Furui, Takuya Fujie, Masahito Ohue, Youming Liu, Sora Nakamura, Kota Nakanishi, Kazunori Okada, Katsumi Maenaka, Minoru Ueda   +12 more
doaj   +1 more source

MGDB: a curated database for molecular glues

Nucleic Acids Research
Abstract Molecular glues (MGs) represent a unique class of small molecules that modulate protein–protein interactions by altering target protein surface properties, enabling targeted degradation, pathway modulation, or functional control of proteins, including traditionally undruggable targets.
Chenxin Li, Haolin Luo, Yu Pang, Yun Liu, Yutao Luo, Xinni Liang, Hongyi Li, Wennuo Li, Ling Wang   +8 more
openaire   +2 more sources

glue-viz/glue: v1.19.1

<p><!-- Release notes generated using configuration in .github/release.yml at main --></p> <h2>What's Changed</h2> <h3>Bug Fixes</h3> <ul> <li>Fix bugs with attribute display units by @astrofrog in ...
Jon Carifio, Chris Beaumont, Thomas Robitaille, Simon Conseil, Yuval Langer, Maarten Breddels, Nabil Freij, Dan D'Avella, Samuel Bennett, Peter Teuben, ejeschke, Robin Wilson, Brigitta Sipőcz, Jonathan Foster, P. L. Lim, Stuart Mumford, Adam Ginsburg, Brett M. Morris, Jonathan Eisenhamer, Derek Homeier, specmicp, Robel Geda, Jeffrey SubbaRao, Will Dampier, Adrian Price-Whelan, Kyle Conroy, Clément Robert, Jesse Averbukh, Ricky O'Steen, John ZuHone   +29 more
core   +1 more source

Out‐of‐Plane Strain‐Decoupled Architecture for High‐Fill‐Factor Stretchable OLED Displays

Advanced Functional Materials, EarlyView.
A vertically decoupled multilayer SOLED architecture separates emissive pixel islands from deformable interconnects, allowing low‐modulus elastomeric layers to accommodate applied strain and suppress strain transfer to the OLED region. This design, combined with transparent hybrid encapsulation, enables a high fill factor (∼75%), stretchability ...
Young Hyun Son, Kyung Cheol Choi, Jeong Hyun Kwon   +2 more
wiley   +1 more source

Design and Characterization of a Novel eEF2K Degrader with Potent Therapeutic Efficacy Against Triple‐Negative Breast Cancer

Advanced Science
Dysregulated eEF2K expression is implicated in the pathogenesis of many human cancers, including triple‐negative breast cancer (TNBC), making it a plausible therapeutic target.
Changxin Zhong, Rongfeng Zhu, Ting Jiang, Sheng Tian, Xiaobao Zhao, Xiaoya Wan, Shilong Jiang, Zonglin Chen, Rong Gong, Linhao He, Jin‐Ming Yang, Na Ye, Yan Cheng   +12 more
doaj   +1 more source