Results 71 to 80 of about 3,265,759 (283)
The B30.2/SPRY-Domain: A Versatile Binding Scaffold in Supramolecular Assemblies of Eukaryotes
CrystalsB30.2 domains, sometimes referred to as PRY/SPRY domains, were originally identified by sequence profiling methods at the gene level. The B30.2 domain comprises a concanavalin A-like fold consisting of two twisted seven-stranded anti-parallel β-sheets ...
Peer R. E. Mittl, Hans-Dietmar Beer
doaj +1 more source
Does fibrin glue prevent biliary and pancreatic fistula after surgical resection? [PDF]
, 2012 Background/Aims: Efficacy of fibrin glue to prevent biliary or pancreas fistula at the resected edge of the liver or pancreas is controversial. We examined surgical results of fibrin glue use in patients who underwent hepatectomy or pancreatectomy to ...
Nanashima, Atsushi +7 more
core +1 more source
Advanced Functional Materials, EarlyView.ABSTRACT Chitosan, a polysaccharide upcycled from biowaste, has long promised sustainable, biocompatible, and antimicrobial films and devices, an appeal reinforced by its recent regulatory recognition, with several chitosan‐based antibacterial dressings gaining clearance through the Food and Drug Administration's 510(k) pathway.
Jacopo Nicoletti +16 more
wiley +1 more source
INSIGHTS INTO MOLECULAR GLUE DEGRADERS: A REVIEW [PDF]
Al-Azhar Journal of Pharmaceutical SciencesResearchers in drug discovery are continually investigating new approaches to develop potential anticancer agents that are effective, safe, tolerable, and exhibit reduced resistance.
Mohamed Ayman El-Zahabi +2 more
doaj +1 more source
Photoswitchable Molecular Glue for DNA
, 2016 DNA molecular glue is a small synthetic ligand that can adhere two single-stranded DNAs that do not spontaneously hybridize with each other. For reversible control of DNA hybridization by an external light stimulus, we have developed a photoswitchable ...
Shin-nosuke Uno (2474065) +2 more
core +1 more source
Advances in Sustainable and Wearable Textile Based Soft Robotics
Advanced Functional Materials, EarlyView.This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas +6 more
wiley +1 more source
PharmaceuticalsChemically induced proximity (CIP) has revolutionized small-molecule pharmacology by moving beyond traditional occupancy-based inhibition and activation.
Linfeng Li +4 more
doaj +1 more source
MolGlueDB: an online database of molecular glues
Nucleic Acids ResearchAbstract Molecular glue degraders (MGDs) and proteolysis-targeting chimeras (PROTACs) are two prominent approaches in targeted protein degradation, both leveraging the ubiquitin-proteasome system to induce selective protein degradation.
Xiao Wang +13 more
openaire +3 more sources
The molecular evolution of spiggin nesting glue in sticklebacks [PDF]
Molecular Ecology, 2015 AbstractGene duplication and subsequent divergence can lead to the evolution of new functions and lineage‐specific traits. In sticklebacks, the successive duplication of a mucin gene (MUC19) into a tandemly arrayed, multigene family has enabled the production of copious amounts of ‘spiggin’, a secreted adhesive protein essential for nest construction ...
Seear, P.J. +3 more
openaire +4 more sources
Biodegradable and Biocompatible Functional Polymers for Biomedical Applications
Advanced Functional Materials, EarlyView.Biodegradable and biocompatible functional polymers integrate electrical, mechanical, and stimuli‐responsive functionalities while enabling programmed degradation under physiological conditions. This review introduces recent advances in conductive, shape‐memory, self‐healing, photocurable, and adhesive polymer systems, emphasizing material design ...
Won Bae Han +5 more
wiley +1 more source