Results 161 to 170 of about 446,524 (307)

MG-DIFF: A novel molecular graph diffusion model for molecular generation and optimization. [PDF]

PLoS One
Zhang X, Wang S, Fang Y, Zhang Q.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Knowledge-aware contrastive heterogeneous molecular graph learning. [PDF]

PLoS Comput Biol
Chen M, Wu J, Pan S, Lin F, Du B, Gong X, Hu W.   +6 more
europepmc   +1 more source

KGE-UNIT: Towards the unification of molecular interactions prediction based on knowledge graph and multi-task learning on drug discovery

, 2023
Zhangchengcheng
openalex   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

GraphGIM: rethinking molecular graph contrastive learning via geometry image modeling. [PDF]

BMC Biol
Li C, Xiang H, Du W, Ma T, Chen H, Zeng X, Xu L.   +6 more
europepmc   +1 more source

An analysis on the Wiener number and the spectrum of detour matrix of the molecular graph of benzenoid hydrocarbons

, 2019
Pananghat Gayathri, T. Ragavan
openalex   +2 more sources

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa, Iago Pinal‐Fernandez, Pritikanta Paul, Michael P. Skolka, Margherita Milone, Min Shi, Mithun V. Shah, Maria Casal‐Dominguez, Katherine Pak, Andrew L. Mammen, Teerin Liewluck   +10 more
wiley   +1 more source

Fingerprint-enhanced hierarchical molecular graph neural networks for property prediction. [PDF]

J Pharm Anal
Liu S, Chen M, Yao X, Liu H.
europepmc   +1 more source

Schultz Polynomial, Modified Schultz Polynomial and Indices of Molecular Graph of Anthracene Based On Domination

, 2019
G. Jayalalitha, M. Raji
openalex   +1 more source