Results 171 to 180 of about 455,903 (307)

MG-DIFF: A novel molecular graph diffusion model for molecular generation and optimization. [PDF]

PLoS One
Zhang X, Wang S, Fang Y, Zhang Q.
europepmc   +1 more source

Additional file 1 of Graph latent diffusion-based molecular representation learning for enhanced generalization in molecular property prediction

Daiki Koge, Naoaki Ono, Takashi Abe, Shigehiko Kanaya   +3 more
openalex   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Knowledge-aware contrastive heterogeneous molecular graph learning. [PDF]

PLoS Comput Biol
Chen M, Wu J, Pan S, Lin F, Du B, Gong X, Hu W.   +6 more
europepmc   +1 more source

The chemical structure and corresponding molecular graph of chloroquine, respectively [37].

Yeliz Kara (21395459), Yeşim Saǧlam Özkan (21395462), Asad Ullah (4524541), Yasser Salah Hamed (21395465), Melaku Berhe Belay (20036542)   +4 more
openalex   +1 more source

molecular graph theory

, 2014
Citation: 'molecular graph theory' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.MT07070 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

GraphGIM: rethinking molecular graph contrastive learning via geometry image modeling. [PDF]

BMC Biol
Li C, Xiang H, Du W, Ma T, Chen H, Zeng X, Xu L.   +6 more
europepmc   +1 more source

An analysis on the Wiener number and the spectrum of detour matrix of the molecular graph of benzenoid hydrocarbons

, 2019
Pananghat Gayathri, T. Ragavan
openalex   +2 more sources

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source