Results 81 to 90 of about 3,947,894 (203)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Molecular hydrogen in the technology of artificial insemination of cows

Siberian Journal of Life Sciences and Agriculture
Background.  Cryopreservation of sperm from cattle is an effective method of breeding work. To increase the efficiency of cryopreservation, the improvement of synthetic diluents for freezing sperm is required.
Marina N. Ivashchenko, Anna V. Deryugina, Alexey I. Erzutov, Vladimir A. Petrov, Andrey A. Belov   +4 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Global modelling of H₂ mixing ratios and isotopic compositions with the TM5 model [PDF]

, 2011
The isotopic composition of molecular hydrogen (H2) contains independent information for constraining the global H2 budget. To explore this, we have implemented hydrogen sources and sinks, including their stable isotopic composition and isotope ...
Langenfelds, R.L., G. Pieterse, T. Röckmann, L. P. Steele, Pieterse, G., Afd Marine and Atmospheric Research, Marine and Atmospheric Research, Steele, L.P., Röckmann, T., Krummel, P.B., Sub Atmospheric physics and chemistry, M. C. Krol, P. B. Krummel, Krol, M.C., R. L. Langenfelds, A. M. Batenburg, Batenburg, A.M.   +16 more
core   +3 more sources

The Energetic Aspect of the Formation of Molecular Hydrogen During Gamma Irradiation of Liquid Cyclohexane

Hydrogen
Molecular hydrogen, the basis of hydrogen energy, is formed in many physical and chemical processes, including the absorption of gamma-ray energy by liquid cyclohexane.
Igor Y. Shchapin, Andrey I. Nekhaev
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Harmonizing hydrogen nanobubbles with ammonia: molecular perspectives on a novel fuel

Data Availability: The data of this paper can be accessed from the Brunel University London data archive, figshare at https://brunel.figshare.com.Supplementary data are available online at: https://www.sciencedirect.com/science/article/pii ...
Wang, X, Mistry, S
core   +1 more source

Combined Molecular Hydrogen and Vitamin C Treatment in Irradiated Normal and Cancer Cell Models: An Exploratory In Vitro Study and Case Reports

Medical Sciences
Background: Radiation therapy is widely used to treat cancer but frequently causes normal tissue toxicities that compromise patients’ quality of life, highlighting the need for strategies that protect healthy tissue without reducing antitumor efficacy ...
Michiko Miyakawa, Songbai Zhang, Jinan Behnan, Yu Ivy Zhang, Claudia Morganti, Keisuke Ito, Pauline Isakson, Per Uhlén, Ayako Miyakawa   +8 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source