Results 91 to 100 of about 5,958,984 (296)
Prospects of molecular imaging
Cancer Imaging, 2011 Modern radiotherapy techniques heavily rely on high-quality medical imaging. Increased accuracy to deliver the dose to tumours while sparing normal tissues demands more precise delineation of the tumours. When considering to deliver a boost to more aggressive parts of tumours, intratumoral heterogeneity needs to be assessed accurately.
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Molecular interferometric imaging
Optics Express, 2008 Common-path in-line shearing interferometry, combined with pixel-array imaging, provides a surface metrology that achieves 15 pm surface height resolution. An eighth-wave thermal oxide on silicon generates a reference wave locked in the condition of phase quadrature for phase-to-intensity conversion that makes surface height or index variations ...
Zhao, M., Wang, X. F., Nolte, D. D.
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Scientific ReportsThe ketogenic diet (KD) has been shown to be effective in refractory epilepsy after long-term administration. However, its interference with short-term brain metabolism and its involvement in the early process leading to epilepsy remain poorly understood.
Matthieu Doyen +10 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Utilizing the enhanced permeability and retention (EPR) effect : theranostic star polymers
, 2019 Introduction: The targeting of tumor cells often relies on the availability of cancer-associated biomarkers at the tumor site. In general, however, expression levels of such biomarkers are unknown at initial diagnosis.
Davis, Thomas P. +10 more
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FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
, 2009 The 4th European Molecular Imaging Meeting, Barcelona, Spain, 27-30 May ...
Liang, J +5 more
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
, 2009 The 4th European Molecular Imaging Meeting, Barcelona, Spain, 27-30 May ...
Liang, J +5 more
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