Results 91 to 100 of about 12,274,852 (362)

Molecular imaging in endoscopy [PDF]

United European Gastroenterology Journal, 2013
Molecular imaging focuses on the molecular signature of cells rather than morphological changes in the tissue. The need for this novel type of imaging arises from the often difficult detection and characterization especially of small and/or premalignant lesions.
Michael S, Hoetker, Martin, Goetz
openaire   +2 more sources

Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT

Cancer Imaging, 2022
This review describes the main benefits of using long axial field of view (LAFOV) PET in clinical applications. As LAFOV PET is the latest development in PET instrumentation, many studies are ongoing that explore the potentials of these systems, which ...
Joyce van Sluis, Ronald Borra, Charalampos Tsoumpas, Johannes H. van Snick, Mostafa Roya, Dik ten Hove, Adrienne H. Brouwers, Adriaan A. Lammertsma, Walter Noordzij, Rudi A.J.O. Dierckx, Riemer H.J.A. Slart, Andor W.J.M. Glaudemans   +11 more
doaj   +1 more source

Cellular solid-state Nuclear Magnetic Resonance spectroscopy

, 2012
Decrypting the structure, function, and molecular interactions of complex molecular machines in their cellular context and at atomic resolution is of prime importance for understanding fundamental physiological processes.
Sub NMR Spectroscopy, Dep Biologie, Molecular Microbiology, Tommassen, J.P.M., NMR Spectroscopy, Post, J.A., Baldus, M., Sub Molecular Microbiology, Renault, M.A.M., Sub Biomolecular Imaging, Bos, M.P., Biomolecular Imaging, Tommassen-van Boxtel, H.A.M.   +12 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

High-speed centrifugation induces aggregation of extracellular vesicles [PDF]

Journal of Extracellular Vesicles, 2015
Plasma and other body fluids contain cell-derived extracellular vesicles (EVs), which participate in physiopathological processes and have potential biomedical applications.
Romain Linares, Sisareuth Tan, Céline Gounou, Nicolas Arraud, Alain R. Brisson   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

High-Performance Molecular Imaging with MALDI Trapped Ion-Mobility Time-of-Flight (timsTOF) Mass Spectrometry

Analytical Chemistry, 2019
Imaging mass spectrometry (IMS) enables the spatially targeted molecular assessment of biological tissues at cellular resolutions. New developments and technologies are essential for uncovering the molecular drivers of native physiological function and ...
J. Spraggins, Katerina V. Djambazova, Emilio S. Rivera, L. Migas, Elizabeth K. Neumann, A. Fuetterer, J. Suetering, Niels Goedecke, A. Ly, R. Van de Plas, R. Caprioli   +10 more
semanticscholar   +1 more source

Comparison of integrin α v β 3 expression with 68Ga-NODAGA-RGD PET/CT and glucose metabolism with 18F-FDG PET/CT in esophageal or gastroesophageal junction cancers

European Journal of Hybrid Imaging, 2023
Background The primary aims of this study were to compare in patients with esophageal or esophagogastric junction cancers the potential of 68Ga-NODAGA-RGD PET/CT with that of 18F-FDG PET/CT regarding tumoral uptake and distribution, as well as ...
Matthieu Dietz, Vincent Dunet, Styliani Mantziari, Anastasia Pomoni, Ricardo Dias Correia, Nathalie Testart Dardel, Sarah Boughdad, Marie Nicod Lalonde, Giorgio Treglia, Markus Schafer, Niklaus Schaefer, John O. Prior   +11 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Molecular interferometric imaging

Optics Express, 2008
Common-path in-line shearing interferometry, combined with pixel-array imaging, provides a surface metrology that achieves 15 pm surface height resolution. An eighth-wave thermal oxide on silicon generates a reference wave locked in the condition of phase quadrature for phase-to-intensity conversion that makes surface height or index variations ...
Zhao, M., Wang, X. F., Nolte, D. D.
openaire   +2 more sources