Results 101 to 110 of about 12,274,852 (362)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
European Journal of Nuclear Medicine and Molecular Imaging, 2019 PurposeDiverse radionuclide imaging techniques are available for the diagnosis, staging, and follow-up of phaeochromocytoma and paraganglioma (PPGL). Beyond their ability to detect and localise the disease, these imaging approaches variably characterise ...
D. Taïeb +14 more
semanticscholar +1 more source
Molecular imaging of bacterial infections: Overcoming the barriers to clinical translation
Science Translational Medicine, 2019 Molecular imaging could fulfill unmet clinical needs for diagnosing and monitoring bacterial infections, if translational barriers are addressed. Clinical diagnostic tools requiring direct sample testing cannot be applied to infections deep within the ...
A. Ordonez +7 more
semanticscholar +1 more source
Molecular imaging in the second near-infrared window
Advanced Functional Materials, 2019 In the past decade, noticeable progress has been achieved regarding fluorescence imaging in the second near‐infrared (NIR‐II) window. Fluorescence imaging in the NIR‐II window demonstrates superiorities of deep tissue penetration and high spatial and ...
Hao Wan, Haotian Du, Feifei Wang, H. Dai
semanticscholar +1 more source
JACC: Cardiovascular Imaging, 2009 Molecular imaging aims to enable personalized medicine via imaging-specific molecular and cellular targets that are relevant to the diagnosis and treatment of disease. By providing in vivo readouts of biological detail, molecular imaging complements traditional anatomical imaging modalities to allow: 1) visualization of important disease-modulating ...
Osborn, Eric A., Jaffer, Farouc A.
openaire +4 more sources
Recent advances in molecular imaging with gold nanoparticles
Bioconjugate chemistry, 2019 Gold nanoparticles (AuNP) have been extensively developed as contrast agents, theranostic platforms and probes for molecular imaging. This popularity has yielded a large number of AuNP designs that vary in size, shape, surface functionalization and ...
M. Bouché +5 more
semanticscholar +1 more source
Mass spectrometry imaging for spatially resolved multi-omics molecular mapping
npj ImagingThe recent upswing in the integration of spatial multi-omics for conducting multidimensional information measurements is opening a new chapter in biological research.
Hua Zhang +5 more
semanticscholar +1 more source
Molecular imaging of fibrosis: recent advances and future directions
Journal of Clinical Investigation, 2019 Fibrosis, the progressive accumulation of connective tissue that occurs in response to injury, causes irreparable organ damage and may result in organ failure.
Sydney B. Montesi +3 more
semanticscholar +1 more source
Molecular imaging in oncology [PDF]
Cancer Imaging, 2004 Cancer is a genetic disease that manifests in loss of normal cellular homeostatic mechanisms. The biology and therapeutic modulation of neoplasia occurs at the molecular level. An understanding of these molecular processes is therefore required to develop novel prognostic and early biomarkers of response. In addition to clinical applications, increased
openaire +2 more sources