Results 141 to 150 of about 12,274,852 (362)

Multimodal Molecular Imaging: Current Status and Future Directions

Contrast Media & Molecular Imaging, 2018
Molecular imaging has emerged at the end of the last century as an interdisciplinary method involving in vivo imaging and molecular biology aiming at identifying living biological processes at a cellular and molecular level in a noninvasive manner.
Min Wu, J. Shu
semanticscholar   +1 more source

The Future of Molecular Imaging

JACC: Cardiovascular Imaging, 2011
Section Editor: Christopher M. Kramer, MD THE PARADOX OF MOLECULAR IMAGING is one that is on the minds of many in the imaging community today. The promise of agents that would identify local biological processes such as inflammation, remodeling, angiogenesis, and metabolism is what attracts ...
Sinusas, Albert J., Thomas, James D., Mills, George   +2 more
openaire   +2 more sources

International consensus on clinical use of presynaptic dopaminergic positron emission tomography imaging in parkinsonism.

Presynaptic dopaminergic positron emission tomography (PET) imaging serves as an essential tool in diagnosing and differentiating patients with suspected parkinsonism, including idiopathic Parkinson's disease (PD) and other neurodegenerative and non ...
Prior, J.O., Dou, X., Cahid Civelek, A., Zhou, R., Li, X., Wang, J., Carrio, I., Kang, K.W., Murakami, K., Tian, M., Watanabe, Y., Zhong, Y., Jin, C., Lu, J., Zuo, C., Zhang, H., Yu, C., Liu, F.   +17 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Development and performance of the small-animal R-SPECT prototype [PDF]

, 2009
[Poster] 4th European Molecular Imaging Meeting, Barcelona, Spain, May 27 - 30, 2009In vivo molecular imaging of small animals has become an essential technique in biomedical research since the introduction of dedicated PeT and SPeCT scanners.
Lage, Eduardo, Villena, José L., Abella García, Mónica, Desco Menéndez, Manuel, Desco, Manuel, Lage Negro, Eduardo, Tapias, Gustavo, Vaquero López, Juan José, Vidal Migallón, I., Carlos, Álvaro de, Vaquero, Juan José, Abella, Mónica, Sisniega, Alejandro, Vidal-Migallón, I.   +13 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, Volume 20, Issue 6, Page 1453-1472, June 2026.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Antibody or Antibody Fragments: Implications for Molecular Imaging and Targeted Therapy of Solid Tumors

Frontiers in Immunology, 2017
The use of antibody-based therapeutics has proven very promising for clinical applications in cancer patients, with multiple examples of antibodies and antibody–drug conjugates successfully applied for the treatment of solid tumors and lymphomas.
Katerina T. Xenaki, S. Oliveira, P. M. P. van Bergen en Henegouwen   +2 more
semanticscholar   +1 more source

Affibody-Modified Gd@C-Dots with Efficient Renal Clearance for Enhanced MRI of EGFR Expression in Non-Small-Cell Lung Cancer [Corrigendum]

International Journal of Nanomedicine
Wu Y, Li H, Yan Y, et al. Int J Nanomedicine. 2020;15:4691—4703. The authors have advised due to an error that occurred inadvertently at the time of figure assembly, the MRI images at the 2 hour time point in Figure 6A and the 10 minute time ...
Wu Y, Li H, Yan Y, Wang K, Cheng Y, Li Y, Zhu X, Xie J, Sun X   +8 more
doaj  

First clinical experience with a dedicated PET for hanging breast molecular imaging

, 2013
[EN] Aim. Recently, a high-resolution dedicated PET system for hanging breast imaging (MAMMI PET) has been developed to improve primary tumor detection and characterization.
Caballero Ontanaya, Luis, Vogel, W., Vrancken Peeters, Marie-Jeanne, Rutgers, Emiel, Valdés Olmos, Renato, Aukema, T. S., Vroonland, Colinda, González Martínez, Antonio Javier, Koolen, Bas, Benlloch Baviera, Jose María   +9 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1513-1534, June 2026.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source