Results 131 to 140 of about 5,958,984 (296)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Chemistry of Molecular Imaging [PDF]

Accounts of Chemical Research, 2009
Meade TJ, AIME, Silvio
openaire   +3 more sources

Polymer-based hybrid biomaterials for gene delivery and imaging

, 2012
1
김원종, 김현우, 남궁란
core  

Therapy-induced modulation of tumor vasculature and oxygenation in a murine glioblastoma model quantified by deep learning-based feature extraction

Scientific Reports
Glioblastoma presents characteristically with an exuberant, poorly functional vasculature that causes malperfusion, hypoxia and necrosis. Despite limited clinical efficacy, anti-angiogenesis resulting in vascular normalization remains a promising ...
Nadine Bauer, Daniel Beckmann, Dirk Reinhardt, Nicole Frost, Stefanie Bobe, Raghu Erapaneedi, Benjamin Risse, Friedemann Kiefer   +7 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Anatomical and molecular imaging of skin cancer

, 2008
Hao Hong1, Jiangtao Sun1, Weibo Cai1,21Departments of Radiology and Medical Physics, School of Medicine and Public Health, University of Wisconsin – Madison, Madison, Wisconsin, USA; 2University of Wisconsin Paul P. Carbone Comprehensive Cancer
Jiangtao Sun, Hao Hong, Weibo Cai
core  

One section, two worlds: single-cell integration of MALDI-MSI and spatial transcriptomics on the same single tissue section

Scientific Reports
Understanding tissue complexity requires spatially resolved multi-omics data at single-cell resolution. Here, we present a workflow integrating high-resolution matrix-assisted laser desorption ionization mass spectrometry imaging (MALDI-MSI) with Xenium ...
Tim F. E. Hendriks, Gert B. Eijkel, Theodoros Visvikis, Benjamin Balluff, Ron M. A. Heeren, Eva Cuypers   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Assessment of Lean body mass using whole-body low-dose Ct from Pet/Ct to identify cancer Cachexia

Cancer Imaging
Introduction Cancer cachexia is a multifactorial syndrome characterised by involuntary weight loss and muscle wasting, commonly seen in patients with advanced malignancies.
G. J. O’Keefe, C. Senko, S. T. Lee, S. J. Gong, S. Pillai, R. Fogliaro, T. Chen, G. Ninatti, K. Pathmaraj, Z. Cao, I. Burvenich, L. Osellame, N. Hoogenraad, A. M. Scott   +13 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source