Results 221 to 230 of about 11,582,729 (334)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

MR molecular imaging for monitoring and predicting tumor responses to immunotherapy. [PDF]

Theranostics
Laney VEA, Zhao W, Hwang IM, Hampson E, Dong J, Hall RC, Weber-Bonk K, Yuan X, Delaney E, Gilmore H, Keri R, Winter J, Wang LL, Lu ZR.   +13 more
europepmc   +1 more source

Enhancing PET Signal at Target Tissue in Vivo: Dendritic and Multimeric Tris(hydroxypyridinone) Conjugates for Molecular Imaging of α_vβ₃ Integrin Expression with Gallium-68

, 2016
Cinzia Imberti, Samantha Y.A. Terry, Carleen Cullinane, Fiona Clarke, Georgina H. Cornish, Nisha K. Ramakrishnan, Peter Roselt, Andrew P. Cope, Rodney J. Hicks, Philip J. Blower, Michelle Ma   +10 more
openalex   +1 more source

An Adenovirus with Enhanced Infectivity Mediates Molecular Chemotherapy of Ovarian Cancer Cells and Allows Imaging of Gene Expression [PDF]

, 2001
Akseli Hemminki, Н. В. Белоусова, Kurt R. Zinn, Bin Liu, Minghui Wang, Tandra R. Chaudhuri, Buck E. Rogers, Donald J. Buchsbaum, Gene P. Siegal, Mack N. Barnes, Jesús Gómez-Navarro, David T. Curiel, Ronald D. Alvarez   +12 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Advances in Molecular Imaging for Neuroendocrine Neoplasms. [PDF]

Cancers (Basel)
Girod B, Prasad V.
europepmc   +1 more source

In vivomolecular imaging of colorectal cancer using quantum dots targeted to vascular endothelial growth factor receptor 2 and optical coherence tomography/laser-induced fluorescence dual-modality imaging [PDF]

, 2015
Jordan L. Carbary-Ganz, Weston A. Welge, Jennifer K. Barton, Urs Utzinger   +3 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Molecular Imaging of Pulmonary Fibrosis. [PDF]

J Nucl Med
Allison MB, Catana C, Zhou IY, Caravan P, Montesi SB.   +4 more
europepmc   +1 more source

Molecular contrast of EGFR expression using gold nanoparticles as a reflectance-based imaging probe

, 2007
James Chen Yong Kah, Malini Olivo, Caroline Lee, Colin J. R. Sheppard   +3 more
openalex   +2 more sources