Results 221 to 230 of about 1,741,453 (344)

The Role of Molecular Imaging in Precision Oncology. [PDF]

J Nucl Med
Bading JR, Mortimer JE.
europepmc   +1 more source

Near-Field Optics and Spectroscopy for Molecular Nano-Imaging [PDF]

, 2004
Satoshi Kawata, Yasushi Inouye, Taro Ichimura   +2 more
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Nanomaterial-Based Molecular Imaging in Cancer: Advances in Simulation and AI Integration. [PDF]

Biomolecules
Chow JCL.
europepmc   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Development of Galectin-7-Specific Nanobodies: Implications for Immunotherapy and Molecular Imaging in Cancer. [PDF]

J Med Chem
Nehmé R, Fortier M, Létourneau M, Fuselier C, Granger Joly de Boissel P, Dumoulin A, Guérin B, Dumulon-Perreault V, Ait-Mohand S, Sarrhini O, Larda ST, Castellanos Villamizar Y, Bernier M, Porębska N, Opaliński Ł, Chatenet D, Doucet N, St-Pierre Y.   +17 more
europepmc   +1 more source

Fluorescence Imaging of Two-Photon Linear Dichroism: Cholesterol Depletion Disrupts Molecular Orientation in Cell Membranes [PDF]

, 2004
Richard K.P. Benninger, Björn Önfelt, Mark A. A. Neil, Daniel M. Davis, Paul M. W. French   +4 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Beyond the Lumen: Molecular Imaging to Unmask Vulnerable Coronary Plaques. [PDF]

J Cardiovasc Dev Dis
Currie G, Kiat H.
europepmc   +1 more source

Tight‐Binding Description of the STM Image of Molecular Chains [PDF]

, 2004
Yoel Calev, Hezy Cohen, Gianaurelio Cuniberti, Abraham Nitzan, Danny Porath   +4 more
openalex   +1 more source