Results 251 to 260 of about 12,274,852 (362)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Artificial intelligence for radiopharmaceutical and molecular imaging. [PDF]

Acta Pharm Sin B
Tao J, Liang L, Hao S, Chen Y, Yang Z, Cai Y, Zhu H.   +6 more
europepmc   +1 more source

Metastatic Meningioma: Neuroradiologic and Molecular Imaging Perspectives. [PDF]

Radiol Imaging Cancer
Rai P, Mehta T, Kumar SS, Choi R, Manupipatpong S, Schick J, Beauchamp N, Lakhani DA, Khan M.   +8 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Molecular Imaging in Parathyroid Carcinoma Management: A Comprehensive Review. [PDF]

Life (Basel)
Petranović Ovčariček P, Giovanella L, Tuncel M, Inukai JI, Liberini V, Romić M, Deandreis D, Ruggeri RM, Vocaturo F, Campennì A, Huellner MW.   +10 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Pathological Mechanisms and Molecular Imaging Advances in Alzheimer's Disease. [PDF]

Clin Interv Aging
Liu C, Meng Y, Liu R, Wang Z, Zhao H.
europepmc   +1 more source

A hybrid molecular-imaging model for high-accuracy early colorectal cancer diagnosis. [PDF]

J Gastrointest Oncol
Zhao Y, Zeng W.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A Look Behind the Paper: Glypican-3-targeted US Molecular Imaging of Hepatocellular Carcinoma. [PDF]

Radiol Imaging Cancer
Liang X, Li L, Wang Y, Lu S, Han X, Yan F, Zhou J.   +6 more
europepmc   +1 more source