Results 51 to 60 of about 11,582,729 (334)

Long-term Ashtanga yoga practice decreases medial temporal and brainstem glucose metabolism in relation to years of experience

EJNMMI Research, 2020
Background Yoga is increasingly popular worldwide with several physical and mental benefits, but the underlying neurobiology remains unclear. Whereas many studies have focused on pure meditational aspects, the triad of yoga includes meditation, postures,
June van Aalst, Jenny Ceccarini, Georg Schramm, Donatienne Van Weehaeghe, Ahmadreza Rezaei, Koen Demyttenaere, Stefan Sunaert, Koen Van Laere   +7 more
doaj   +1 more source

Sparse image reconstruction for molecular imaging

, 2008
The application that motivates this paper is molecular imaging at the atomic level. When discretized at sub-atomic distances, the volume is inherently sparse.
Hero III, Alfred O., Raich, Raviv, Ting, Michael   +2 more
core   +1 more source

124-Color Super-resolution Imaging by Engineering DNA-PAINT Blinking Kinetics [PDF]

, 2019
Optical super-resolution techniques reach unprecedented spatial resolution down to a few nanometers. However, efficient multiplexing strategies for the simultaneous detection of hundreds of molecular species are still elusive.
Ganji, M., Grabmayr, H., Jungmann, R., Nickels, P., Schnitzbauer, J., Schueder, F., Schwille, P., Stehr, F., Stein, J., Strauss, M., Strauss, S., Wade, O., Woehrstein, J., Yin, P.   +13 more
core   +3 more sources

Human biodistribution and internal dosimetry of 4-[ 18 F]fluorobenzyl-dexetimide: a PET radiopharmaceutical for imaging muscarinic acetylcholine receptors in the brain and heart

EJNMMI Research, 2020
Background 4-[18F] fluorobenzyl dexetimide (F-DEX) is the first non-subtype selective fluorine-18 labelled tracer for muscarinic receptors (mAChR) used in humans. A recent first-in-human study found high regional brain uptake with low variation in normal
Cameron D. Pain, Graeme J. O’Keefe, Uwe Ackermann, Vincent Dore, Victor L. Villemagne, Christopher C. Rowe   +5 more
doaj   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source

Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections

Nature Communications, 2020
Sensitive diagnostic tools for bacterial infections of wounds and surgical sites are necessary to enable early detection and determine optimal means of treatment.
Aimen Zlitni, Gayatri Gowrishankar, Idan Steinberg, Tom Haywood, Sanjiv Sam Gambhir   +4 more
doaj   +1 more source

Sapap3 deletion causes dynamic synaptic density abnormalities: a longitudinal [11C]UCB-J PET study in a model of obsessive–compulsive disorder-like behaviour

EJNMMI Research, 2020
Background Currently, the evidence on synaptic abnormalities in neuropsychiatric disorders—including obsessive–compulsive disorder (OCD)—is emerging. The newly established positron emission tomography (PET) ligand ((R)-1-((3-((11)C-methyl-(11)C)pyridin-4-
Dorien Glorie, Jeroen Verhaeghe, Alan Miranda, Stef De Lombaerde, Sigrid Stroobants, Steven Staelens   +5 more
doaj   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Imaging the Breakdown of Molecular-Frame Dynamics through Rotational Uncoupling

, 2017
We demonstrate the breakdown of molecular-frame dynamics induced by the uncoupling of molecular rotation from electronic motion in molecular Rydberg states. We observe this non-Born-Oppenheimer regime in the time domain through photoelectron imaging of a
Bucksbaum, Philip H., Natan, Adi, Zipp, Lucas J.   +2 more
core   +1 more source