Results 111 to 120 of about 1,221,694 (269)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Punctual mutations in lipoxygenase sequence expressed in black soybean seed coat

open access: yesJournal of Seed Science
Lipoxygenase enzymes are relevant in several characteristics of soybean seeds, such as germination performance, storage capacity and tolerance to infection by microorganisms.
Liliane Marcia Mertz   +5 more
doaj  

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Immunologic and molecular analysis for low-grade malt lymphoma: Are there any useful markers to predict the outcome after Helicobacter pylori irradication? [PDF]

open access: bronze, 1998
Yumi Matsushima   +8 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Fire blight (Erwinia amylovora) resistance in apple varieties associated with molecular markers

open access: hybrid, 2009
Jasna Sehic   +5 more
openalex   +2 more sources

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