DNA methylation dynamics in aging: How far are we from understanding the mechanisms? [PDF]
, 2018 DNA methylation is currently the most promising molecular marker for monitoring aging and predicting life expectancy. However, the mechanisms underlying age-related DNA methylation changes remain mostly undiscovered.Here we discuss the current knowledge ...
Caiafa, Paola +3 more
core +1 more source
Evolution of an ancient protein function involved in organized multicellularity in animals. [PDF]
, 2016 To form and maintain organized tissues, multicellular organisms orient their mitotic spindles relative to neighboring cells. A molecular complex scaffolded by the GK protein-interaction domain (GKPID) mediates spindle orientation in diverse animal taxa ...
Anderson, Douglas P +8 more
core +2 more sources
FSTL5 expression is a marker of Group C metastatic medulloblastomas [PDF]
, 2014 INTRODUCTION: Medulloblastoma (MB) is the most commonmalignant brain tumor in children. Four different molecular subgroups are recognized, which differ in gene expression, genomic aberrations, histology, demographics and survival:WNT and SHH groups ...
Baldi, Caterina +5 more
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Meningioma classification by immunohistochemistry: A replicability study
Brain and Spine, 2023 Introduction: Meningiomas account for nearly 40% of intracranial tumors. Recently, the immunohistochemistry (IHC) markers S100B, SCGN, ACADL and MCM2 have been shown to be associated with underlying biological subtypes of meningioma (MG1-MG4).
Olivia Näslund +7 more
doaj +1 more source
The gyrB gene is a useful phylogenetic marker for exploring the diversity of flavobacterium strains isolated from terrestrial and aquatic habitats in Antarctica [PDF]
, 2011 Within the phylum Bacteroidetes, the gyrB gene, encoding for the B subunit of the DNA gyrase, has been used as phylogenetic marker for several genera closely related to Flavobacterium.
Peeters, Karolien, Willems, Anne
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Lectin ligands: New insights into their conformations and their dynamic behavior and the discovery of conformer selection by lectins [PDF]
, 1998 The mysteries of the functions of complex glycoconjugates have enthralled scientists over decades. Theoretical considerations have ascribed an enormous capacity to store information to oligosaccharides, In the interplay with lectins sugar-code words of ...
Bovin, N. V. +11 more
core +4 more sources
Genetic structure among four populations of paddlefish, Polyodon spathula (Actinopterygii: Acipenseriformes: Polyodontidae), based on disomic microsatellite markers [PDF]
Acta Ichthyologica et Piscatoria, 2014 Background. The paddlefish, Polyodon spathula (Walbaum, 1792), is an important species for commercial and recreational fisheries throughout the central United States.
X. Zheng +5 more
doaj +3 more sources
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Future breeding for organic and low-input agriculture: integrating values and modern breeding tools for improving robustness [PDF]
, 2010 Organic production and also the attention for plant breeding for organic agriculture is still increasing in Europe. The question often raised is how much does plant breeding for the organic sector differ from modern plant breeding and does a ban on GMO ...
Lammerts van Bueren, E.T.
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Understanding the evolution of native pinewoods in Scotland will benefit their future management and conservation [PDF]
, 2010 Scots pine (Pinus sylvestris L.) is a foundation species in Scottish highland forests and a national icon. Due to heavy exploitation, the current native pinewood coverage represents a small fraction of the postglacial maximum.
Barton +22 more
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