Results 31 to 40 of about 7,421,514 (390)

Loss of Neuroprotective Factors in Neurodegenerative Dementias: The End or the Starting Point?

open access: yesFrontiers in Neuroscience, 2017
Recent clinical, genetic and biochemical experimental evidences highlight the existence of common molecular pathways underlying neurodegenerative diseases.
Luisa Benussi   +3 more
doaj   +1 more source

Prodromal frontotemporal dementia: clinical features and predictors of progression

open access: yesAlzheimer’s Research & Therapy, 2021
Background The prodromal phase of frontotemporal dementia (FTD) is still not well characterized, and conversion rates to dementia and predictors of progression at 1-year follow-up are currently unknown.
Alberto Benussi   +9 more
doaj   +1 more source

High-Throughput Sequencing Strategy for Microsatellite Genotyping Using Neotropical Fish as a Model

open access: yesFrontiers in Genetics, 2018
Genetic diversity and population studies are essential for conservation and wildlife management programs. However, monitoring requires the analysis of multiple loci from many samples. These processes can be laborious and expensive.
Juliana S. M. Pimentel   +9 more
doaj   +1 more source

Reduced Intensity Conditioning for Allogeneic Stem Cell Transplantation (HSCT) in Acute Myeloid Leukemia

open access: yesHematology, Transfusion and Cell Therapy, 2022
Allogeneic transplantation (HSCT) is an effective curative therapy for high risk acute myeloid leukemia (AML) which account for 38% of the transplants in Europe (1). Prior to HSCT, a conditioning or preparative regimen is administered.
Arnon Nagler
doaj   +1 more source

Inventory of molecular markers affecting biological characteristics of avian influenza A viruses

open access: yesVirus genes, 2019
Avian influenza viruses (AIVs) circulate globally, spilling over into domestic poultry and causing zoonotic infections in humans. Fortunately, AIVs are not yet capable of causing sustained human-to-human infection; however, AIVs are still a high risk as ...
A. Suttie   +5 more
semanticscholar   +1 more source

Genetic and genomic approaches for the discovery of parasite genes involved in antimalarial drug resistance [PDF]

open access: yes, 2013
The biggest threat to the war on malaria is the continued evolution of drug resistance by the parasite. Resistance to almost all currently available antimalarials now exists in Plasmodium falciparum which causes the most suffering among all human malaria
Mwangi, J.M., Ranford-Cartwright, L.C.
core   +1 more source

DNA molecular markers in plant breeding: current status and recent advancements in genomic selection and genome editing

open access: yes, 2018
With the development of molecular marker technology in the 1980s, the fate of plant breeding has changed. Different types of molecular markers have been developed and advancement in sequencing technologies has geared crop improvement.
M. Nadeem   +12 more
semanticscholar   +1 more source

Genetic counselling and testing for inherited dementia: single-centre evaluation of the consensus Italian DIAfN protocol

open access: yesAlzheimer’s Research & Therapy, 2020
Background A consensus protocol for genetic counselling and testing of familial dementia, the Italian Dominantly Inherited Alzheimer’s and Frontotemporal Network (IT-DIAfN) protocol, has been developed in Italy by a network of expert dementia centres ...
Anna Mega   +9 more
doaj   +1 more source

In vivo detection of lamellocytes in Drosophila melanogaster. [PDF]

open access: yes, 2009
Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila, the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific ...
Brand   +17 more
core   +1 more source

Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease

open access: yesActa Neuropathologica Communications, 2018
One of the earliest pathological features characterizing Alzheimer’s disease (AD) is the loss of dendritic spines. Among the many factors potentially mediating this loss of neuronal connectivity, the contribution of Rho-GTPases is of particular interest.
Mirta Borin   +15 more
doaj   +1 more source

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